This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.We have been breeding sufficient meadow voles to conduct the experiment. We now have the 40 meadow voles needed for this experiment. These voles will be used as an animal model to examine the relationship between affiliative behavior and alcohol consumption. Monogamous prairie voles are highly social and also consume much higher amounts of alcohol than other rodents. The hypothesis is that similar neurological mechanisms regulate the rewarding aspects of alcohol use and affiliative behavior and therefore animals that are more affiliative will display higher alcohol intake. A series of studies in prairie voles are underway at the Oregon Health and Sciences University to examine the relationship between affiliative behavior and alcohol consumption in prairie voles. The project at Yerkes is a subcontract of the larger project and will examine alcohol consumption in relatively asocial meadow voles with the goal of comparing alcohol intake with prairie voles.
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