This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Associate Director for Research Services oversees activities in the Primate Center s five service units. As always, the organization and presence of different Units continues to be dynamic, and responsive to the needs of the investigators and cutting edge science. In 2005 the five Units consisted of Assay, Genetics, Pathology, Virology and Immunology, and Centralized Protocol Implementation (CPI) Services. Changes include moving the Genetics portion out of Immunogenetics and Virology and moving Library Services to the newly formed Information Services. Both moves indicate the success and increasing need for the services of each Unit. In the case of the Genetics Service, the technology and user base expanded rapidly when the activities in the Genetics Resource became part of the Service Unit of Immunogenetics and Virology. Given this increase in Unit activities, it became apparent that an independent Unit Head was needed, and one was appointed. In a similar manner, the expansion of information technology and use of the same in relation to the Center required formation of Information Services, the description of which is detailed elsewhere in this document. The CPI Service Unit continues to expand, and had a smooth transition when the administrative Unit Head retired in July and was replaced by a former colony manager with a doctorate degree in animal behavior. In 2005 both Assay and Pathology Services had major equipment purchases move from primarily developmental to full chargeback status. The high-pressure liquid chromatography system in Assay Services was used to measure multiple steroids in low concentrations for endocrinology studies and perform peptide identification for developmental studies. The Pathology Unit s confocal system with 4 visible light lasers and the pulsed near infrared laser for multiphoton excitation is being increasing utilized by stem cell investigators and developmental biologists as well as AIDS investigato
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