This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To provide core, campus and non-host investigators with organized and efficient WNPRC and UW-Madison resources, protocol management and expertise. Progress and Concerns Since May 2008, CPI again has supported 41 different projects this year involving 23 investigators (10 WNPRC core scientists, 8 UW affiliates, 4 affiliates from other academic institutions, and 1 investigator from the private sector). We are also in the process of starting 3 new projects (1 UW affiliate, 2 other academic affiliates). There were changes in the types of projects as some ended and others began. In addition, different investigators left the UW and were replaced by other UW affiliates. Since the total number of projects remained the same, this may be an indication of the capabilities of support that the CPI unit and the primate resource are able to maintain at any one time. It will be interesting to see how this changes as CPI continues in it's fourth year. Allocation of Resource Access Projects must fall within the mission of WNPRC, be approved by the director and executive committee, and WNPRC have the resources to provide support. In addition, CPI emphasizes three core areas that match the major research areas and resources at WNPRC and identified three core scientist co-investigators for consultation in the respective cores. Dissemination (All Divisions and Units) In addition to the WNPRC web site, we rely on recommendations by core and affiliate scientists. We are also sending CPI staff to annual scientific meetings to present what resources and techniques are available to the scientific members in attendance. Training (All Divisions and Units) The veterinary head of CPI is responsible for all training of CPI personnel for the multitude of procedures cited above and utilizes other members of Veterinary Services and the university as needed. Written instruction as well as hands-on training and oversight of procedures to assure proficiency are utilized to provide a highly skilled technical staff to researchers. A manual with over 50 detailed SOPs is maintained by the unit to provide detailed guides for simple and complex procedures in the areas of reproduction, sample procurement, treatment, behavior, observation, training, imaging, processing and shipping. We continue to improve on our comprehensive system of technician training documentation to assure that our staff is appropriately cross-trained in as many research areas as possible. Virtually all publications relying on WNPRC resources in part or in full involved the use of the CPI Unit. Note: AIDS related.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Primate Research Center Grants (P51)
Project #
5P51RR000167-48
Application #
7958777
Study Section
Special Emphasis Panel (ZRR1-CM-8 (01))
Project Start
2009-05-01
Project End
2010-04-30
Budget Start
2009-05-01
Budget End
2010-04-30
Support Year
48
Fiscal Year
2009
Total Cost
$98,295
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
Other Domestic Higher Education
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Kang, HyunJun; Mesquitta, Walatta-Tseyon; Jung, Ho Sun et al. (2018) GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition. Stem Cell Reports 11:197-211
Rhoads, Timothy W; Burhans, Maggie S; Chen, Vincent B et al. (2018) Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys. Cell Metab 27:677-688.e5
Ellis-Connell, Amy L; Balgeman, Alexis J; Zarbock, Katie R et al. (2018) ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment. J Virol 92:
Park, Mi Ae; Jung, Ho Sun; Slukvin, Igor (2018) Genetic Engineering of Human Pluripotent Stem Cells Using PiggyBac Transposon System. Curr Protoc Stem Cell Biol 47:e63
Mattison, Julie A; Colman, Ricki J; Beasley, T Mark et al. (2017) Caloric restriction improves health and survival of rhesus monkeys. Nat Commun 8:14063
Feltovich, Helen (2017) Cervical Evaluation: From Ancient Medicine to Precision Medicine. Obstet Gynecol 130:51-63
Singaravelu, Janani; Zhao, Lian; Fariss, Robert N et al. (2017) Microglia in the primate macula: specializations in microglial distribution and morphology with retinal position and with aging. Brain Struct Funct 222:2759-2771
Ellis, Amy; Balgeman, Alexis; Rodgers, Mark et al. (2017) Characterization of T Cells Specific for CFP-10 and ESAT-6 in Mycobacterium tuberculosis-Infected Mauritian Cynomolgus Macaques. Infect Immun 85:
Rodrigues, Michelle A (2017) Female Spider Monkeys (Ateles geoffroyi) Cope with Anthropogenic Disturbance Through Fission-Fusion Dynamics. Int J Primatol 38:838-855
Buechler, Connor R; Bailey, Adam L; Lauck, Michael et al. (2017) Genome Sequence of a Novel Kunsagivirus (Picornaviridae: Kunsagivirus) from a Wild Baboon (Papio cynocephalus). Genome Announc 5:

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