Rhesus monkeys (M mulatta) infected with the lentivirus, SIV, develop an immunodeficiency syndrome with marked similarities to HIV infection in humans Approximately 70% of experimentally SIV-infected animals succumb to AIDS within one year, although the disease varies with virus strain, and the immune response of the host We are using in situ hybridization with probes to SIV, SRV-1, CMV, EBV, Herpes saimiri, parvovirus, and SV40 to study tissue localization in primary retroviral- induced lesions and lesions induced by opportunistic infections in macaques experimentally infected with different strains of SIV

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Primate Research Center Grants (P51)
Project #
5P51RR000168-41
Application #
6591335
Study Section
Project Start
2002-05-01
Project End
2003-04-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
41
Fiscal Year
2002
Total Cost
$111,112
Indirect Cost
Name
Harvard University
Department
Type
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
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