This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To determine whether social stress affects SIV disease progression and AIDS following establishment of viral set point, and the mechanisms involved, and to generate pilot data on whether drugs that block the action of stress-response systems can ameliorate the effects of social stress on SIV disease progression.
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