The Administrative Core will provide the scientific leadership and administrative support for this AlcoholResearch Center (ARC). It will direct the scientific review of and start and termination of approved pilotprojects, and the funding of new pilot projects (if unspent funds become available) after appropriate review.It will provide a central source of statistical expertise, and will provide guidance in the interpretation of themicroarray data provided from the Genomics and Molecular Biology Core. It will monitor the progress of allresearch components and core activities. In all these matters, the advice of a Program Advisory Committeeconsisting of extramural and intramural scientists will be sought. It will serve the investigators in fiscalplanning and procurement and personnel management. It will authorize and provide funds for travel and payfor publishing costs. It will provide leadership in organizing seminars, conferences, and workshops and indissemination of new research knowledge to the academic and lay communities. It will seek to develop newcollaborations within the School and University; it will also foster collaborative research ventures between theIARC and other ARCs and investigators in this country and abroad. It will support the TranslationalResearch and Science Education component as it develops educational programs aimed at health careproviders, and outreach activities for members of the judiciary and local alcohol treatment providers, and willadd to the capabilities and value of the Center's web site. It will participate in the recruitment and careerdevelopment of a junior alcohol reserachers, and seek to attract promising individuals into the field.Public Health Relevance: Alcohol abuse and alcoholism are major public health issues. The researchcarried out by the investigators in the Indiana ARC will help us better understand the neurobiological basis ofalcohol preference and craving, the role of genes implicated in the risk of alcoholism on responses toalcohol, and the mechanisms that are responsible for the fetal alcohol syndrome. It will take a leadership rolein development of educational materials related to the science of alcohol addiction for health care workers(nurses, social workers, and physicians) as well as attorneys and judges
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