application) DESCRIPTION:
The specific aims of this OAIC are to: 1) conduct intervention development studies (IDS) designed to improve the function and independence of older Americans recovering from stroke; 2) integrate studies of clinical outcomes with studies of underlying physiologic, biomechanical, and psychosocial mechanisms of stroke recovery; 3) foster multidisciplinary research and research training related to independence in older Americans, with a special focus on geriatric rehabilitation; and 4) disseminate information about stroke, disability and rehabilitation to the lay and professional public. The three IDS include 1) """"""""Improving Recovery After Stroke"""""""", which is a randomized clinical trial of a physiologically based, twelve-week program of therapeutic exercise in 180 stroke survivors. The study is designed to improve key impairments, functional limitations and disabilities; 2) """"""""Attention and Motor Learning After Stroke"""""""", which is a cross-sectional and cohort study of attentional deficits and their influence on motor learning in stroke survivors and healthy older adults; and 3) """"""""Neural Bases for Recovery of Function After Stroke"""""""", which is a study of the relationship between motor recovery and functional reorganization in the motor cortex of adult nonhuman primates following vascular infarcts. The two research resources cores include a stroke registry and recruitment core and a design and analysis core. The latter core provides data management, communications, biostatistical and economic-analysis services. This OAIC will use project leaders (PL) from four schools and faculty from 12 departments. The long-term goals of the center are to: 1) establish effective, multidisciplinary interventions for stroke rehabilitation that can be implemented in clinical practice; 2) improve recovery in older adults with disabilities by fostering mechanistic and outcomes research in geriatric rehabilitation; and 3) encourage multidisciplinary collaboration by integrating basic and applied research and research training of diverse disciplines.
| Woodbury, Michelle L; Velozo, Craig A; Richards, Lorie G et al. (2013) Rasch analysis staging methodology to classify upper extremity movement impairment after stroke. Arch Phys Med Rehabil 94:1527-33 |
| Plummer-D'Amato, Prudence; Altmann, Lori J P; Behrman, Andrea L et al. (2010) Interference between cognition, double-limb support, and swing during gait in community-dwelling individuals poststroke. Neurorehabil Neural Repair 24:542-9 |
| Rogalski, Yvonne; Altmann, Lori J P; Plummer-D'Amato, Prudence et al. (2010) Discourse coherence and cognition after stroke: a dual task study. J Commun Disord 43:212-24 |
| Plummer-D'Amato, Prudence; Altmann, Lori J P; Saracino, Dawn et al. (2008) Interactions between cognitive tasks and gait after stroke: a dual task study. Gait Posture 27:683-8 |
| Woodbury, Michelle L; Velozo, Craig A; Richards, Lorie G et al. (2008) Longitudinal stability of the Fugl-Meyer Assessment of the upper extremity. Arch Phys Med Rehabil 89:1563-9 |
| Friel, Kathleen M; Barbay, Scott; Frost, Shawn B et al. (2007) Effects of a rostral motor cortex lesion on primary motor cortex hand representation topography in primates. Neurorehabil Neural Repair 21:51-61 |
| Schmid, Arlene; Duncan, Pamela W; Studenski, Stephanie et al. (2007) Improvements in speed-based gait classifications are meaningful. Stroke 38:2096-100 |
| Pohl, Patricia S; McDowd, Joan M; Filion, Diane et al. (2007) Task switching after stroke. Phys Ther 87:66-73 |
| Woodbury, Michelle L; Velozo, Craig A; Richards, Lorie G et al. (2007) Dimensionality and construct validity of the Fugl-Meyer Assessment of the upper extremity. Arch Phys Med Rehabil 88:715-23 |
| Pohl, P S; McDowd, J M; Filion, D et al. (2006) Implicit learning of a motor skill after mild and moderate stroke. Clin Rehabil 20:246-53 |
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