Abstract

The aim of the Research Development Core (RDC) is to develop and support a high quality research and training program for the enhancement and improvement of independence of older Americans. Five pilot projects analyze the physiological development of age-associated muscle atrophy (sarcopenia). They serve as the basis for a multi-disciplinary research and training program designed to develop junior faculty and post-doctoral fellows who are deeply committed to academic careers in geriatrics and gerontology.
The specific aims of the RDC are to: 1. Provide a structured research and didactic training program in gerontology and geriatrics for career development of promising junior faculty and post-doctoral fellows. 2. Promote the growth of research on aging at UTMB by encouraging established investigators in other fields to turn their efforts to aging research by (a) mentoring pilot research projects relevant to OAIC; (b) incorporate aging issues in their research programs and (c) assisting in the development of interdisciplinary aging research projects to the OAIC. By teaming mentors and trainee investigators on pilot projects, and through interactions with senior investigators, the RDC offers a comprehensive training program that spans from detailed mechanistic studies based on animal models to clinical interventions.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
1P60AG017231-01
Application #
6323722
Study Section
Special Emphasis Panel (ZAG1-BJB-9 (A9))
Project Start
2000-02-01
Project End
2005-01-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2000
Total Cost
$159,185
Indirect Cost

  Institution

Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555

  Publications

Mittal, Sahil; Lin, Yu-Li; Tan, Alai et al. (2014) Limited life expectancy among a subgroup of medicare beneficiaries receiving screening colonoscopies. Clin Gastroenterol Hepatol 12:443-450.e1
Tuvdendorj, Demidmaa; Chinkes, David L; Zhang, Xiao-Jun et al. (2011) Skeletal muscle is anabolically unresponsive to an amino acid infusion in pediatric burn patients 6 months postinjury. Ann Surg 253:592-7
Symons, T B; Sheffield-Moore, M; Mamerow, M M et al. (2011) The anabolic response to resistance exercise and a protein-rich meal is not diminished by age. J Nutr Health Aging 15:376-81
Fisher, Steve R; Kuo, Yong-fang; Graham, James E et al. (2010) Early ambulation and length of stay in older adults hospitalized for acute illness. Arch Intern Med 170:1942-3
Sharma, Gulshan; Fletcher, Kathlyn E; Zhang, Dong et al. (2009) Continuity of outpatient and inpatient care by primary care physicians for hospitalized older adults. JAMA 301:1671-80
Rabek, Jeffrey P; Hafer-Macko, Charlene E; Amaning, James K et al. (2009) A proteomics analysis of the effects of chronic hemiparetic stroke on troponin T expression in human vastus lateralis. J Gerontol A Biol Sci Med Sci 64:839-49
Symons, T Brock; Sheffield-Moore, Melinda; Wolfe, Robert R et al. (2009) A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc 109:1582-6
Alfaro-Acha, Ana; Al Snih, Soham; Raji, Mukaila A et al. (2007) Does 8-foot walk time predict cognitive decline in older Mexicans Americans? J Am Geriatr Soc 55:245-51
Fujita, Satoshi; Rasmussen, Blake B; Bell, Jill A et al. (2007) Basal muscle intracellular amino acid kinetics in women and men. Am J Physiol Endocrinol Metab 292:E77-83
Cree, Melanie G; Newcomer, Bradley R; Read, Laura K et al. (2007) Plasma triglycerides are not related to tissue lipids and insulin sensitivity in elderly following PPAR-alpha agonist treatment. Mech Ageing Dev 128:558-65

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