Abstract

The Nurses' Health Study (NHS) is an ongoing epidemiologic study of 121,700 female U.S. registered nurses, aged 30-55 years in 1976. The NHS is the largest population-based cohort used for rheumatic disease epidemiology and has been used to test hypotheses in systemic rheumatic conditions such as RA and SLE. Osteoarthritis (OA) has not been studied in this cohort because of the expense and the difficulties inherent in its case definition. The present proposal is to conduct a study of the validity of a self-reported diagnosis of knee OA and hip OA among a subset of women from the NHS, allowing us to demonstrate the feasibility of a large scale study of dietary and hormonal predictors of self- reported OA in the NHS.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
5P60AR036308-15
Application #
6100416
Study Section
Project Start
1999-04-01
Project End
2000-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
15
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Koch-Weser, Susan; Rudd, Rima E; Dejong, William (2010) Quantifying word use to study health literacy in doctor-patient communication. J Health Commun 15:590-602
Simard, Julia F; Karlson, Elizabeth W; Costenbader, Karen H et al. (2008) Perinatal factors and adult-onset lupus. Arthritis Rheum 59:1155-61
Costenbader, Karen H; Feskanich, Diane; Mandl, Lisa A et al. (2006) Smoking intensity, duration, and cessation, and the risk of rheumatoid arthritis in women. Am J Med 119:503.e1-9
Karlson, E W; Costenbader, K H; McAlindon, T E et al. (2005) High sensitivity, specificity and predictive value of the Connective Tissue Disease Screening Questionnaire among urban African-American women. Lupus 14:832-6
Katz, Jeffrey N; Amick 3rd, Benjamin C; Keller, Robert et al. (2005) Determinants of work absence following surgery for carpal tunnel syndrome. Am J Ind Med 47:120-30
Costenbader, Karen H; Kim, Daniel J; Peerzada, Jehanna et al. (2004) Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis. Arthritis Rheum 50:849-57
Karlson, Elizabeth W; Liang, Matthew H; Eaton, Holley et al. (2004) A randomized clinical trial of a psychoeducational intervention to improve outcomes in systemic lupus erythematosus. Arthritis Rheum 50:1832-41
Bischoff-Ferrari, H A; Lingard, E A; Losina, E et al. (2004) Psychosocial and geriatric correlates of functional status after total hip replacement. Arthritis Rheum 51:829-35
Iversen, Maura D; Fossel, Anne H; Ayers, Kelly et al. (2004) Predictors of exercise behavior in patients with rheumatoid arthritis 6 months following a visit with their rheumatologist. Phys Ther 84:706-16
Karlson, Elizabeth W; Mandl, Lisa A; Hankinson, Susan E et al. (2004) Do breast-feeding and other reproductive factors influence future risk of rheumatoid arthritis? Results from the Nurses' Health Study. Arthritis Rheum 50:3458-67

Showing the most recent 10 out of 242 publications