Abstract

The major goal of this core facility is to expand our capabilities in analytical microscopy to all relevant studies in arthritis and musculoskeletal diseases. The specific objectives of the Analytical microscopy Core are; 1. To efficiently provide morphological techniques and analysis for the study of soft and hard tissues, at the light and electron microscopic levels, for research programs involving investigators within the Hospital for Special Surgery - Cornell medical Center. 2. To provide information to all investigators regarding the use of new techniques in histology, histochemistry, immunocytochemistry and morphometry. 3. To develop our capacity for systematic and quantitative evaluation of fixed an living cells analyzed by microscopic techniques. 4. To develop new applications of microscopic techniques to fit the research programs of investigators within the arthritis an musculoskeletal diseases research base. With this cooperative effort, the investigators can design their experiments to take advantage of specific analytical microscopic techniques essential to progress in their studies.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
5P60AR038520-09
Application #
5206197
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Abraido-Lanza, Ana F; Revenson, Tracey A (2006) Illness intrusion and psychological adjustment to rheumatic diseases: a social identity framework. Arthritis Rheum 55:224-32
Peterson, Margaret G E; Blake, Valerie A; Allegrante, John P et al. (2004) A comparison of self-reported hip symptomatology in hip replacement patients and a population-based sample of medicare beneficiaries. Med Sci Monit 10:CR275-81
Blake, Valerie A; Allegrante, John P; Robbins, Laura et al. (2002) Racial differences in social network experience and perceptions of benefit of arthritis treatments among New York City Medicare beneficiaries with self-reported hip and knee pain. Arthritis Rheum 47:366-71
Ruchlin, H S; Elkin, E B; Allegrante, J P (2001) The economic impact of a multifactorial intervention to improve postoperative rehabilitation of hip fracture patients. Arthritis Rheum 45:446-52
Mancuso, C A; Paget, S A; Charlson, M E (2000) Adaptations made by rheumatoid arthritis patients to continue working: a pilot study of workplace challenges and successful adaptations. Arthritis Care Res 13:89-99
Peterson, M G; Allegrante, J P; Augurt, A et al. (2000) Major life events as antecedents to hip fracture. J Trauma 48:1096-100
Muller, W A; Randolph, G J (1999) Migration of leukocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes. J Leukoc Biol 66:698-704
Pricop, L; Gokhale, J; Redecha, P et al. (1999) Reactive oxygen intermediates enhance Fc gamma receptor signaling and amplify phagocytic capacity. J Immunol 162:7041-8
Liao, F; Schenkel, A R; Muller, W A (1999) Transgenic mice expressing different levels of soluble platelet/endothelial cell adhesion molecule-IgG display distinct inflammatory phenotypes. J Immunol 163:5640-8
Mancuso, C A (1999) Impact of new guidelines on physicians' ordering of preoperative tests. J Gen Intern Med 14:166-72

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