The primary goal of the Center for Hearing Loss in Children is to improve the future prospects of children with all degrees of hearing loss, from mild to profound, through a tightly integrated program of research, research training, continuing education and information dissemination. All programs of the Center, including the six proposed research projects, are organized around three overall themes: 1) early identification of educationally significant hearing loss, 2) the effective remediation of educationally significant hearing loss, and 3) understanding the causes of hearing loss in children with the ultimate goal of prevention and treatment. Because both research and clinical practice in the field of childhood hearing loss entail multidisciplinary efforts, the Research Program will employ techniques drawn from behavioral research, genetics, and neurobiology. A Research Training Program for trainees ranging from undergraduates to postdoctoral fellows will be offered in all areas of research conducted by the Center. Special emphasis will be placed on recruiting students who are deaf, hard of hearing, or members of underrepresented minority groups. The Continuing Education Program is targeted at the diverse group of professionals who serve children with hearing loss. The Information Dissemination Program is designed to provide parents with information on a variety of topics related to raising a child with hearing loss and to educate the public about identification, causes, and consequences of childhood hearing loss and how to prevent it. The Information Dissemination Program complements the Research Training Program with a unique effort to inform parents, counselors, and students with hearing loss about career opportunities in the communication sciences.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Comprehensive Center (P60)
Project #
2P60DC000982-06
Application #
2126186
Study Section
Special Emphasis Panel (ZDC1-SRB-S (06))
Project Start
1990-09-30
Project End
2000-08-31
Budget Start
1995-09-01
Budget End
1996-08-31
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Father Flanagan's Boys' Home
Department
Type
DUNS #
City
Boys Town
State
NE
Country
United States
Zip Code
68010
Song, Lei; McGee, Joann; Walsh, Edward J (2008) The influence of thyroid hormone deficiency on the development of cochlear nonlinearities. J Assoc Res Otolaryngol 9:464-76
Song, Lei; McGee, JoAnn; Walsh, Edward J (2008) Development of cochlear amplification, frequency tuning, and two-tone suppression in the mouse. J Neurophysiol 99:344-55
Varga, R; Avenarius, M R; Kelley, P M et al. (2006) OTOF mutations revealed by genetic analysis of hearing loss families including a potential temperature sensitive auditory neuropathy allele. J Med Genet 43:576-81
Song, Lei; McGee, Jo Ann; Walsh, Edward J (2006) Consequences of combined maternal, fetal and persistent postnatal hypothyroidism on the development of auditory function in Tshrhyt mutant mice. Brain Res 1101:59-72
Song, Lei; McGee, Joann; Walsh, Edward J (2006) Frequency- and level-dependent changes in auditory brainstem responses (ABRS) in developing mice. J Acoust Soc Am 119:2242-57
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Pennings, Ronald J E; Topsakal, Vedat; Astuto, Lisa et al. (2004) Variable clinical features in patients with CDH23 mutations (USH1D-DFNB12). Otol Neurotol 25:699-706
Varga, R; Kelley, P M; Keats, B J et al. (2003) Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) gene. J Med Genet 40:45-50
Higgins, Maureen B; McCleary, Elizabeth A; Carney, Arlene Earley et al. (2003) Longitudinal changes in children's speech and voice physiology after cochlear implantation. Ear Hear 24:48-70
Bhattacharya, Gautam; Miller, Caroline; Kimberling, William J et al. (2002) Localization and expression of usherin: a novel basement membrane protein defective in people with Usher's syndrome type IIa. Hear Res 163:1-11

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