The Clinical Core provides a centralized resources for not only case ascertainment and description, but also for education outreach to patients and professional in conjunction with the Information Dissemination Core, the development of new information regarding health care utilization by patients with craniofacial anomalies, the implementation of a strong informatics components that will facilitate databasing not only within the center itself but in connection with a large number of other centers and activities and finally, interfaces with new advanced technologies in medical imaging that will be of direct relevance to patient management and care, as well as providing a strong component for projects and pilot projects. This core will be under the direction of Dr. John Canady, who currently serves as the Director of the Craniofacial Anomalies Clinic at the University of Iowa and is uniquely well situated to bridge clinical research and basic science activities. He will be assisted by investigators Dr. Michael Vannier, an international expert in craniofacial imaging, Dr. Mike Karnell, a speech pathologist with a long-standing expertise and interest in craniofacial informatics, and Dr. Petter Damiano, a dentist and health care policy specialist with an interest in outcomes research. Core activities will support databases, clinical case ascertainment and distribution and facilitation of imaging as well as the policy research and patient contacts outlined above.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Comprehensive Center (P60)
Project #
5P60DE013076-03
Application #
6483412
Study Section
Project Start
2001-08-01
Project End
2002-07-31
Budget Start
Budget End
Support Year
3
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Haworth, Simon; Shungin, Dmitry; van der Tas, Justin T et al. (2018) Consortium-based genome-wide meta-analysis for childhood dental caries traits. Hum Mol Genet 27:3113-3127
Govil, Manika; Mukhopadhyay, Nandita; Weeks, Daniel E et al. (2018) Novel caries loci in children and adults implicated by genome-wide analysis of families. BMC Oral Health 18:98
Yang, Jie; Zhu, Wei; Chen, Jiansong et al. (2014) Genome-wide two-marker linkage disequilibrium mapping of quantitative trait loci. BMC Genet 15:20
Beaty, T H; Taub, M A; Scott, A F et al. (2013) Confirming genes influencing risk to cleft lip with/without cleft palate in a case-parent trio study. Hum Genet 132:771-81
Skare, Oivind; Jugessur, Astanand; Lie, Rolv Terje et al. (2012) Application of a novel hybrid study design to explore gene-environment interactions in orofacial clefts. Ann Hum Genet 76:221-36
Wehby, G L; Tyler, M C; Lindgren, S et al. (2012) Oral clefts and behavioral health of young children. Oral Dis 18:74-84
Shaffer, J R; Wang, X; Feingold, E et al. (2011) Genome-wide association scan for childhood caries implicates novel genes. J Dent Res 90:1457-62
Schneider, Galen B; Zaharias, Rebecca; Seabold, Denise et al. (2011) Integrin-associated tyrosine kinase FAK affects Cbfa1 expression. J Orthop Res 29:1443-7
Larjava, H; Koivisto, L; Häkkinen, L et al. (2011) Epithelial integrins with special reference to oral epithelia. J Dent Res 90:1367-76
Jugessur, Astanand; Shi, Min; Gjessing, Håkon Kristian et al. (2010) Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. PLoS One 5:e11493

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