Abstract

The purpose of the Biostatistical Core is to provide consultation services for all investigators in the Comprehensive Center for Oral Health Research of Discovery on issues of study design and data analysis. Drs. Beaty and Lele, both co-investigators in the Johns Hopkins Center for Craniofacial Development and Disorders, will work with investigators on projects that address issues of statistical analysis. In addition, the Biostatistical Core will serve as a referral center for the morphometric analysis needed for Projects IV and VI. Dr. Richtsmeier and Lele will serve as consultants for all morphometric analyses and image data from other clinical centers will be transmitted to Dr. Richtmeier's lab for storage and analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Comprehensive Center (P60)
Project #
1P60DE013078-01
Application #
6159318
Study Section
Project Start
1999-08-01
Project End
2000-07-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Richtsmeier, Joan T (2018) A century of development. Am J Phys Anthropol 165:726-740
Ludwig, Kerstin U; Mangold, Elisabeth; Herms, Stefan et al. (2012) Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet 44:968-71
Taub, Margaret A; Schwender, Holger; Beaty, Terri H et al. (2012) Incorporating genotype uncertainties into the genotypic TDT for main effects and gene-environment interactions. Genet Epidemiol 36:225-34
Hill, Cheryl A; Vaddi, S; Moffitt, Amanda et al. (2011) Intracranial volume and whole brain volume in infants with unicoronal craniosynostosis. Cleft Palate Craniofac J 48:394-8
Aldridge, Kristina (2011) Patterns of differences in brain morphology in humans as compared to extant apes. J Hum Evol 60:94-105
Richtsmeier, J T; Deleon, V B (2009) Morphological integration of the skull in craniofacial anomalies. Orthod Craniofac Res 12:149-58
Frazier, Brenda C; Mooney, Mark P; Losken, H Wolfgang et al. (2008) Comparison of craniofacial phenotype in craniosynostotic rabbits treated with anti-Tgf-beta2 at suturectomy site. Cleft Palate Craniofac J 45:571-82
Park, Ji Wan; McIntosh, Iain; Hetmanski, Jacqueline B et al. (2007) Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations. Genet Med 9:219-27
Parsons, Trish; Ryan, Timothy M; Reeves, Roger H et al. (2007) Microstructure of trabecular bone in a mouse model for Down syndrome. Anat Rec (Hoboken) 290:414-21
Mooney, Mark P; Losken, H Wolfgang; Moursi, Amr M et al. (2007) Postoperative anti-Tgf-beta2 antibody therapy improves intracranial volume and craniofacial growth in craniosynostotic rabbits. J Craniofac Surg 18:336-46;discussion 347-9

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