Abstract

(taken from application): The function of the Biostatistics Core is to achieve and maintain standards of high statistical quality in diabetes-related research and to engage in statistical methodological research. To this end, the Core personnel assist DRTC investigators: 1) in the development of innovative statistical methods to answer questions that arise from the diabetes-related research, 2) in the design of research studies, 3) in the design of data-collection instruments to facilitate data entry and performing of data entry and management for large studies, 4) in the selection and implementation of appropriate statistical analyses, 5) in the preparation of manuscripts using statistical analyses done by Core personnel, 6) in the writing of research grants and 7) to provide statistical support for the Pilot and Feasibility Grant program of the DRTC.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Comprehensive Center (P60)
Project #
5P60DK020542-25
Application #
6564144
Study Section
Project Start
2001-12-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
25
Fiscal Year
2002
Total Cost
$228,547
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Hannon, Tamara S; Kirkman, M S; Patel, Yash R et al. (2014) Profound defects in ?-cell function in screen-detected type 2 diabetes are not improved with glucose-lowering treatment in the Early Diabetes Intervention Program (EDIP). Diabetes Metab Res Rev 30:767-76
Patel, Y R; Kirkman, M S; Considine, R V et al. (2013) Effect of acarbose to delay progression of carotid intima-media thickness in early diabetes. Diabetes Metab Res Rev 29:582-91
Kirkman, M Sue; Shankar, R Ravi; Shankar, Sudha et al. (2006) Treating postprandial hyperglycemia does not appear to delay progression of early type 2 diabetes: the Early Diabetes Intervention Program. Diabetes Care 29:2095-101
Wilson, Wayne A; Wang, Zhong; Roach, Peter J (2005) Regulation of yeast glycogen phosphorylase by the cyclin-dependent protein kinase Pho85p. Biochem Biophys Res Commun 329:161-7
Hermel, Evan; Hart, Andrew J; Gunduz, Irfan et al. (2004) Polymorphism and conservation of the genes encoding Qa1 molecules. Immunogenetics 56:639-49
Pederson, Bartholomew A; Wilson, Wayne A; Roach, Peter J (2004) Glycogen synthase sensitivity to glucose-6-P is important for controlling glycogen accumulation in Saccharomyces cerevisiae. J Biol Chem 279:13764-8
Wilson, Wayne A; Hughes, William E; Tomamichel, Wendy et al. (2004) Increased glycogen storage in yeast results in less branched glycogen. Biochem Biophys Res Commun 320:416-23
Duan, Chaojun; Li, Minghua; Rui, Liangyou (2004) SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin. J Biol Chem 279:43684-91
Shankar, Sudha S; Mirzamohammadi, Bahram; Walsh, James P et al. (2004) L-carnitine may attenuate free fatty acid-induced endothelial dysfunction. Ann N Y Acad Sci 1033:189-97
Thurmond, Debbie C; Gonelle-Gispert, Carmen; Furukawa, Megumi et al. (2003) Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex. Mol Endocrinol 17:732-42

Showing the most recent 10 out of 151 publications