Abstract

The Division of Basic Science Research is responsible for coordinating the activities of the projects in the Division, for enhancing communication among members of the Division, Center, and general scientific community, and for establishing an environment for new interactions and scientific initiatives in the Center. This will be accomplished through a series of seminars, workshops, working meetings, and reports. In addition, the Office will promote review of the activities of the Center through external and internal review programs. Finally, the Office will coordinate the activities of the Diagnostic Laboratory to provide accurate genotypic and phenotypic analysis for patients studied at the Center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Comprehensive Center (P60)
Project #
5P60HL028391-14
Application #
5213393
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Ariens, Robert A S; Lai, Thung-Shenq; Weisel, John W et al. (2002) Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood 100:743-54
Ware, Russell E; Eggleston, Barry; Redding-Lallinger, Rupa et al. (2002) Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy. Blood 99:10-4
Thompson Jr, Robert J; Gustafson, Kathryn E; Bonner, Melanie J et al. (2002) Neurocognitive development of young children with sickle cell disease through three years of age. J Pediatr Psychol 27:235-44
Slaughter, T F; Sreeram, G; Sharma, A D et al. (2001) Reversible shear-mediated platelet dysfunction during cardiac surgery as assessed by the PFA-100 platelet function analyzer. Blood Coagul Fibrinolysis 12:85-93
Lai, T S; Hausladen, A; Slaughter, T F et al. (2001) Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase. Biochemistry 40:4904-10
Ataga, K I; Orringer, E P (2000) Renal abnormalities in sickle cell disease. Am J Hematol 63:205-11
Ataga, K I; Orringer, E P (2000) Bone marrow necrosis in sickle cell disease: a description of three cases and a review of the literature. Am J Med Sci 320:342-7
Kinney, T R; Helms, R W; O'Branski, E E et al. (1999) Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. Blood 94:1550-4
Lai, T S; Slaughter, T F; Peoples, K A et al. (1999) Site-directed mutagenesis of the calcium-binding site of blood coagulation factor XIIIa. J Biol Chem 274:24953-8
Slentz-Kesler, K A; Hale, L P; Kaufman, R E (1998) Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms. Genomics 47:327-40

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