Core - Clinical Research and Statistics

Eckman, James R.

Abstract

A clinical research core has been developed to support the needs of all collaborating investigators in the Center program. the overall objectives of this core are to assist Center investigators in study design, recruit patients for investigative studies, collect required clinical data, supervise the collection and shipment of samples, assist in data collection, storage, analysis, and reporting.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Comprehensive Center (P60)
• Project #: 5P60HL048482-04
• Application #: 5213960
• Support Year: 4
• Fiscal Year: 1996

Publications

Walmet, Paula S; Eckman, James R; Wick, Timothy M (2003) Inflammatory mediators promote strong sickle cell adherence to endothelium under venular flow conditions. Am J Hematol 73:215-24

Montes, Richard A O; Eckman, James R; Hsu, Lewis L et al. (2002) Sickle erythrocyte adherence to endothelium at low shear: role of shear stress in propagation of vaso-occlusion. Am J Hematol 70:216-27

Boni, L C; Brown, R T; Davis, P C et al. (2001) Social information processing and magnetic resonance imaging in children with sickle cell disease. J Pediatr Psychol 26:309-19

Frank, N C; Brown, R T; Blount, R L et al. (2001) Predictors of affective responses of mothers and fathers of children with cancer. Psychooncology 10:293-304

Ievers-Landis, C E; Brown, R T; Drotar, D et al. (2001) Situational analysis of parenting problems for caregivers of children with sickle cell syndromes. J Dev Behav Pediatr 22:169-78

Brown, M D; Wick, T M; Eckman, J R (2001) Activation of vascular endothelial cell adhesion molecule expression by sickle blood cells. Pediatr Pathol Mol Med 20:47-72

Tomer, A; Harker, L A; Kasey, S et al. (2001) Thrombogenesis in sickle cell disease. J Lab Clin Med 137:398-407

Brown, R T; Davis, P C; Lambert, R et al. (2000) Neurocognitive functioning and magnetic resonance imaging in children with sickle cell disease. J Pediatr Psychol 25:503-13

Brown, R T; Lambert, R; Devine, D et al. (2000) Risk-resistance adaptation model for caregivers and their children with sickle cell syndromes. Ann Behav Med 22:158-69

Guasch, A; Zayas, C F; Eckman, J R et al. (1999) Evidence that microdeletions in the alpha globin gene protect against the development of sickle cell glomerulopathy in humans. J Am Soc Nephrol 10:1014-9