Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA010531-02
Application #
2047179
Study Section
Special Emphasis Panel (SRCA (58))
Project Start
1995-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Martin-Fardon, Rémi; Weiss, Friedbert (2017) Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand. Addict Biol 22:923-932
Martin-Fardon, Rémi; Weiss, Friedbert (2013) Modeling relapse in animals. Curr Top Behav Neurosci 13:403-32
Kufahl, Peter R; Martin-Fardon, Rémi; Weiss, Friedbert (2011) Enhanced sensitivity to attenuation of conditioned reinstatement by the mGluR 2/3 agonist LY379268 and increased functional activity of mGluR 2/3 in rats with a history of ethanol dependence. Neuropsychopharmacology 36:2762-73
Braconi, Simone; Sidhpura, Nimish; Aujla, Harinder et al. (2010) Revisiting intragastric ethanol intubation as a dependence induction method for studies of ethanol reward and motivation in rats. Alcohol Clin Exp Res 34:538-44
Sidhpura, Nimish; Weiss, Friedbert; Martin-Fardon, Rémi (2010) Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence. Biol Psychiatry 67:804-11
Gilpin, Nicholas W; Smith, Amanda D; Cole, Maury et al. (2009) Operant behavior and alcohol levels in blood and brain of alcohol-dependent rats. Alcohol Clin Exp Res 33:2113-23
Mason, Barbara J; Shaham, Yavin; Weiss, Friedbert et al. (2009) Stress, alcohol craving, and relapse risk: mechanisms and viable treatment targets. Alcohol 43:541-3
Dayas, Christopher V; McGranahan, Tresa M; Martin-Fardon, Remi et al. (2008) Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse. Biol Psychiatry 63:152-7
Dayas, Christopher V; Liu, Xiu; Simms, Jeffery A et al. (2007) Distinct patterns of neural activation associated with ethanol seeking: effects of naltrexone. Biol Psychiatry 61:979-89
Zhao, Yu; Dayas, Christopher V; Aujla, Harinder et al. (2006) Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala. J Neurosci 26:9967-74

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