Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
1R01AA010536-01A2
Application #
2047186
Study Section
Clinical and Treatment Subcommittee (ALCP)
Project Start
1996-09-15
Project End
1999-08-31
Budget Start
1996-09-15
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mc Lean Hospital (Belmont, MA)
Department
Type
DUNS #
City
Belmont
State
MA
Country
United States
Zip Code
02478
Penetar, David M; Toto, Lindsay H; Lee, David Y-W et al. (2015) A single dose of kudzu extract reduces alcohol consumption in a binge drinking paradigm. Drug Alcohol Depend 153:194-200
Lukas, Scott E; Penetar, David; Su, Zhaohui et al. (2013) A standardized kudzu extract (NPI-031) reduces alcohol consumption in nontreatment-seeking male heavy drinkers. Psychopharmacology (Berl) 226:65-73
Bracken, Bethany K; Penetar, David M; Maclean, Robert Ross et al. (2011) Kudzu root extract does not perturb the sleep/wake cycle of moderate drinkers. J Altern Complement Med 17:961-6
Penetar, David M; Maclean, Robert R; McNeil, Jane F et al. (2011) Kudzu extract treatment does not increase the intoxicating effects of acute alcohol in human volunteers. Alcohol Clin Exp Res 35:726-34
Penetar, David M; McNeil, Jane F; Ryan, Elizabeth T et al. (2008) Comparison among plasma, serum, and whole blood ethanol concentrations: impact of storage conditions and collection tubes. J Anal Toxicol 32:505-10
Penetar, David M; Teter, Christian J; Ma, Zhongze et al. (2006) Pharmacokinetic profile of the isoflavone puerarin after acute and repeated administration of a novel kudzu extract to human volunteers. J Altern Complement Med 12:543-8
Ma, Zhongze; Wu, Qingli; Lee, David Y W et al. (2005) Determination of puerarin in human plasma by high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 823:108-14
Lukas, Scott E; Penetar, David; Berko, Jeff et al. (2005) An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Alcohol Clin Exp Res 29:756-62