Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG008206-03
Application #
3119716
Study Section
Aging Review Committee (AGE)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1989-08-01
Budget End
1990-07-31
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Georgetown University
Department
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Gandy, Sam; Zhang, Yun-wu; Ikin, Annat et al. (2007) Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo. J Neurochem 102:619-26
Mishizen-Eberz, Amanda J; Rissman, Robert A; Carter, Troy L et al. (2004) Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology. Neurobiol Dis 15:80-92
Carter, Troy L; Rissman, Robert A; Mishizen-Eberz, Amanda J et al. (2004) Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage. Exp Neurol 187:299-309
Armstrong, David M; Sheffield, Roxanne; Mishizen-Eberz, Amanda J et al. (2003) Plasticity of glutamate and GABAA receptors in the hippocampus of patients with Alzheimer's disease. Cell Mol Neurobiol 23:491-505
Prybylowski, K L; Wolfe, B B (2000) Developmental differences in alternative splicing of the NR1 protein in rat cortex and cerebellum. Brain Res Dev Brain Res 123:143-50
Kharlamov, A; Kharlamov, E; Armstrong, D M (2000) Age-dependent increase in infarct volume following photochemically induced cerebral infarction: putative role of astroglia. J Gerontol A Biol Sci Med Sci 55:B135-41; discussion B142-3
Wang, Y; TesFaye, E; Yasuda, R P et al. (2000) Effects of post-mortem delay on subunits of ionotropic glutamate receptors in human brain. Brain Res Mol Brain Res 80:123-31
Ikonomovic, M D; Nocera, R; Mizukami, K et al. (2000) Age-related loss of the AMPA receptor subunits GluR2/3 in the human nucleus basalis of Meynert. Exp Neurol 166:363-75
Ikonomovic, M D; Mizukami, K; Warde, D et al. (1999) Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease. Exp Neurol 160:194-204
Mizukami, K; Ikonomovic, M D; Grayson, D R et al. (1998) Immunohistochemical study of GABAA receptor alpha1 subunit in the hippocampal formation of aged brains with Alzheimer-related neuropathologic changes. Brain Res 799:148-55

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