This project will identify basic mechanisms underlying age-related changes in languages - and sequencing in behavior. The experiments test two general accounts of cognitive aging, Transmission Deficit hypothesis and the Inhibitory Deficit hypothesis, and promise to fill in our knowledge regarding relations between aging and comprehension, conceptual error detection, word retrieval, speech errors, and other aspects of language production. The main long-term goal is to help develop well specified theories of aging that apply to a broad spectrum of cognitive performance, and address applied issues related to why older adults commonly experience difficulty in retrieving information, producing speech, and encoding new information in everyday life. Unlike previous approaches focusing primarily on cognitive declines, this project also examines cases where older adults: are predicted to exhibit superior performance to young adults. Five sets of experiments are proposed. Experiments 1-5 investigate effects of aging on the on- line perception of phonology. Experiments 6-8 examine age-linked changes in the ability to encode words and sentences under time pressure. Experiments 7-14 compare effects of aging for participants carrying out directly comparable perception versus production tasks in order to understand age-linked asymmetries between language production and perception, e.g., age-linked declines in word retrieval versus robust comprehension of the same words. Experiments 15-17 are the first to explore effects of aging on the extremely general problem of serial order in the organization of behavior. Experiments 18-23 examine effects of aging on miscomprehensions and the ability to detect conceptual errors.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG009755-10
Application #
6168088
Study Section
Special Emphasis Panel (ZRG2-HUD-2 (03))
Program Officer
Elias, Jeffrey W
Project Start
1991-05-06
Project End
2002-04-30
Budget Start
2000-05-01
Budget End
2001-04-30
Support Year
10
Fiscal Year
2000
Total Cost
$384,448
Indirect Cost
Name
University of California Los Angeles
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
MacKay, Donald G; James, Lori E; Hadley, Christopher B et al. (2011) Speech errors of amnesic H.M.: unlike everyday slips-of-the-tongue. Cortex 47:377-408
MacKay, Donald G; James, Lori E (2009) Visual cognition in amnesic H.M.: selective deficits on the What's-Wrong-Here and Hidden-Figure tasks. J Clin Exp Neuropsychol 31:769-89
MacKay, Donald G; James, Lori E; Hadley, Christopher B (2008) Amnesic H.M.'s performance on the language competence test: parallel deficits in memory and sentence production. J Clin Exp Neuropsychol 30:280-300
MacKay, Donald G; James, Lori E (2004) Sequencing, speech production, and selective effects of aging on phonological and morphological speech errors. Psychol Aging 19:93-107
MacKay, Donald G; Shafto, Meredith; Taylor, Jennifer K et al. (2004) Relations between emotion, memory, and attention: evidence from taboo stroop, lexical decision, and immediate memory tasks. Mem Cognit 32:474-88
James, L E; MacKay, D G (2001) H.M., word knowledge, and aging: support for a new theory of long-term retrograde amnesia. Psychol Sci 12:485-92
MacKay, D G (2001) A tale of two paradigms or metatheoretical approaches to cognitive neuropsychology: did Schmolck, Stefanacci, and Squire (2000) show that hippocampal lesions only impair memory, whereas adjacent (extrahippocampal) lesions impair detection and explanation Brain Lang 78:265-72; discussion 273-5
MacKay, D G; Stewart, R; Burke, D M (1998) H.M. revisited: relations between language comprehension, memory, and the hippocampal system. J Cogn Neurosci 10:377-94
MacKay, D G; Abrams, L; Pedroza, M J et al. (1996) Cross-language facilitation, semantic blindness, and the relation between language and memory: a reply to Altarriba and Soltano. Mem Cognit 24:712-8
MacKay, D G; Miller, M D; Schuster, S P (1994) Repetition blindness and aging: evidence for a binding deficit involving a single, theoretically specified connection. Psychol Aging 9:251-8