Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG010755-05
Application #
2051975
Study Section
Special Emphasis Panel (SRC (34))
Project Start
1991-09-29
Project End
1997-06-30
Budget Start
1995-07-12
Budget End
1997-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Bimonte-Nelson, Heather A; Granholm, Ann-Charlotte E; Nelson, Matthew E et al. (2008) Patterns of neurotrophin protein levels in male and female Fischer 344 rats from adulthood to senescence: how young is ""young"" and how old is ""old""? Exp Aging Res 34:13-26
Granholm, Ann-Charlotte; Boger, Heather; Emborg, Marina E (2008) Mood, memory and movement: an age-related neurodegenerative complex? Curr Aging Sci 1:133-9
Paredes, D; Granholm, A-Ch; Bickford, P C (2007) Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat. Brain Res 1141:56-64
Williams, Brice; Granholm, Ann-Charlotte; Sambamurti, Kumar (2007) Age-dependent loss of NGF signaling in the rat basal forebrain is due to disrupted MAPK activation. Neurosci Lett 413:110-4
French, K L; Bimonte-Nelson, H A; Granholm, A C (2007) Galantamine effects on memory, spatial cue utilization, and neurotrophic factors in aged female rats. Cell Transplant 16:197-205
Williams, Brice J; Bimonte-Nelson, Heather A; Granholm-Bentley, Ann-Charlotte (2006) ERK-mediated NGF signaling in the rat septo-hippocampal pathway diminishes with age. Psychopharmacology (Berl) 188:605-18
Williams, Brice J; Eriksdotter-Jonhagen, Maria; Granholm, Ann-Charlotte (2006) Nerve growth factor in treatment and pathogenesis of Alzheimer's disease. Prog Neurobiol 80:114-28
French, Kristen L; Granholm, Ann-Charlotte E; Moore, Alfred B et al. (2006) Chronic nicotine improves working and reference memory performance and reduces hippocampal NGF in aged female rats. Behav Brain Res 169:256-62
Williams, Brice; Nelson, Matthew; Granholm, Ann-Charlotte et al. (2005) Altered NGF response but not release in the aged septo-hippocampal cholinergic system. Exp Neurol 196:30-40
Bimonte-Nelson, Heather A; Singleton, Rachel S; Nelson, Matthew E et al. (2003) Testosterone, but not nonaromatizable dihydrotestosterone, improves working memory and alters nerve growth factor levels in aged male rats. Exp Neurol 181:301-12

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