Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG012288-03
Application #
2053801
Study Section
Neuroscience, Behavior and Sociology of Aging Review Committee (NBSA)
Project Start
1994-02-10
Project End
1998-12-31
Budget Start
1996-03-05
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
California Institute of Technology
Department
Type
Schools of Arts and Sciences
DUNS #
078731668
City
Pasadena
State
CA
Country
United States
Zip Code
91125
Makino, Clint L; Dodd, R L; Chen, J et al. (2004) Recoverin regulates light-dependent phosphodiesterase activity in retinal rods. J Gen Physiol 123:729-41
Krispel, Claudia M; Chen, Ching-Kang; Simon, Melvin I et al. (2003) Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice. J Neurosci 23:6965-71
Mendez, Ana; Lem, Janis; Simon, Melvin et al. (2003) Light-dependent translocation of arrestin in the absence of rhodopsin phosphorylation and transducin signaling. J Neurosci 23:3124-9
Chen, Ching-Kang; Eversole-Cire, Pamela; Zhang, Haikun et al. (2003) Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. Proc Natl Acad Sci U S A 100:6604-9
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Offermanns, S; Mancino, V; Revel, J P et al. (1997) Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science 275:533-6
Wieland, T; Chen, C K; Simon, M I (1997) The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination. J Biol Chem 272:8853-6

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