Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG013566-02
Application #
2055568
Study Section
Special Emphasis Panel (ZRG4-NTN (06))
Program Officer
Finkelstein, David B
Project Start
1995-07-10
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Biochemistry
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Napoli, Joseph L (2012) Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta 1821:152-67
Kane, Maureen A; Bright, Frank V; Napoli, Joseph L (2011) Binding affinities of CRBPI and CRBPII for 9-cis-retinoids. Biochim Biophys Acta 1810:514-8
Kane, Maureen A; Folias, Alexandra E; Wang, Chao et al. (2010) Ethanol elevates physiological all-trans-retinoic acid levels in select loci through altering retinoid metabolism in multiple loci: a potential mechanism of ethanol toxicity. FASEB J 24:823-32
Chrispell, Jared D; Feathers, Kecia L; Kane, Maureen A et al. (2009) Rdh12 activity and effects on retinoid processing in the murine retina. J Biol Chem 284:21468-77
Chen, Na; Onisko, Bruce; Napoli, Joseph L (2008) The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation. J Biol Chem 283:20841-7
Kane, Maureen A; Folias, Alexandra E; Wang, Chao et al. (2008) Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometry. Anal Chem 80:1702-8
Chen, Na; Napoli, Joseph L (2008) All-trans-retinoic acid stimulates translation and induces spine formation in hippocampal neurons through a membrane-associated RARalpha. FASEB J 22:236-45
Kane, Maureen A; Folias, Alexandra E; Napoli, Joseph L (2008) HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues. Anal Biochem 378:71-9
Kane, Maureen A; Chen, Na; Sparks, Susan et al. (2005) Quantification of endogenous retinoic acid in limited biological samples by LC/MS/MS. Biochem J 388:363-9
McCaffery, Peter; Koul, Omanand; Smith, Deborah et al. (2004) Ethanol increases retinoic acid production in cerebellar astrocytes and in cerebellum. Brain Res Dev Brain Res 153:233-41

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