Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
9R01AG013983-12
Application #
2055924
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1984-12-01
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Hinman, Rochelle M; Smith, Mia J; Cambier, John C (2014) B cells and type 1 diabetes ...in mice and men. Immunol Lett 160:128-32
O'Neill, Shannon K; Getahun, Andrew; Gauld, Stephen B et al. (2011) Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity 35:746-56
Yarkoni, Yuval; Cambier, John C (2011) Differential STIM1 expression in T and B cell subsets suggests a role in determining antigen receptor signal amplitude. Mol Immunol 48:1851-8
Yarkoni, Yuval; Getahun, Andrew; Cambier, John C (2010) Molecular underpinning of B-cell anergy. Immunol Rev 237:249-63
Chan, Marcia A; Gigliotti, Nicole M; Matangkasombut, Ponpan et al. (2010) CD23-mediated cell signaling in human B cells differs from signaling in cells of the monocytic lineage. Clin Immunol 137:330-6
Waterman, Paul M; Cambier, John C (2010) The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms. FEBS Lett 584:4878-82
Cambier, John C; Getahun, Andy (2010) B cell activation versus anergy; the antigen receptor as a molecular switch. Immunol Lett 128:6-7
Getahun, Andrew; O'Neill, Shannon K; Cambier, John C (2009) Establishing anergy as a bona fide in vivo mechanism of B cell tolerance. J Immunol 183:5439-41
O'Neill, Shannon K; Liu, Edwin; Cambier, John C (2009) Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes 16:293-8
Crowley, Jenni E; Stadanlick, Jason E; Cambier, John C et al. (2009) FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation. Blood 113:1464-73

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