Falls continue to be a serious public health concern in the United States, accounting for over 85% of the fractures in older adults, often leading to disability and even death. The objective of this research is to increase our understanding of the influence of aging upon balance by continuing our studies on the role of attention in postural control in older adults. Recent studies have shown that postural control requires increasing attentional effort, particularly in older adults. Our recent research also has shown that balance recovery engages attention rapidly in young and older adults. In this proposal we will focus on understanding how attention is engaged in balance in older adults. We hypothesize that balance engages attention through perceptual channel facilitation/inhibition, central selection/decision mechanisms, and in motor response selection. Further, we hypothesize that aging influences each of these mechanisms. We propose to use dual-task paradigms that vary information processing tasks and balance tasks such that the characteristics of attentional selectivity involved in postural control can be uncovered. This proposed study has four specific aims.
The first aim i s to determine the attentional selectivity in standing postural control in young and older adults; more specifically, to investigate sensory integration, perceptual channel selectivity and the relative roles of facilitation and inhibition.
The second aim i s to investigate the temporal dynamics of attention during balance recovery from rapid perturbations in older adults.
The third aim i s to investigate the influence of attention on motor response selection during balance recovery following postural perturbations.
The fourth aim i s to determine the role of attention in postural responses to moving visual environments. Four experiments are proposed. Each experiment will incorporate different postural tasks and information processing tasks to address the associated hypotheses. This research will lead to a greater understanding of how attention and balance interact and how aging influences that interaction.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
2R01AG014116-05A1
Application #
6579218
Study Section
Special Emphasis Panel (ZRG1-GRM (01))
Program Officer
Finkelstein, Judith A
Project Start
1997-01-01
Project End
2008-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
5
Fiscal Year
2003
Total Cost
$260,823
Indirect Cost
Name
University of Pittsburgh
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Redfern, Mark S; Chambers, April J; Jennings, J Richard et al. (2017) Sensory and motoric influences on attention dynamics during standing balance recovery in young and older adults. Exp Brain Res 235:2523-2531
Fuhrman, Susan I; Redfern, Mark S; Jennings, J Richard et al. (2015) Interference between postural control and spatial vs. non-spatial auditory reaction time tasks in older adults. J Vestib Res 25:47-55
Nunley, Karen A; Ryan, Christopher M; Orchard, Trevor J et al. (2015) White matter hyperintensities in middle-aged adults with childhood-onset type 1 diabetes. Neurology 84:2062-9
Jennings, J Richard; Mendelson, David N; Redfern, Mark S et al. (2011) Detecting age differences in resistance to perceptual and motor interference. Exp Aging Res 37:179-97
Mendelson, David N; Redfern, Mark S; Nebes, Robert D et al. (2010) Inhibitory processes relate differently to balance/reaction time dual tasks in young and older adults. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 17:1-18
Redfern, Mark S; Jennings, J Richard; Mendelson, David et al. (2009) Perceptual inhibition is associated with sensory integration in standing postural control among older adults. J Gerontol B Psychol Sci Soc Sci 64:569-76
Ward, Bryan K; Redfern, Mark S; Jennings, J Richard et al. (2008) The influence of cognitive tasks on vestibular-induced eye movements in young and older adults. J Vestib Res 18:187-95
Muller, Martijn L T M; Redfern, Mark S; Jennings, J Richard (2007) Postural prioritization defines the interaction between a reaction time task and postural perturbations. Exp Brain Res 183:447-56
Landgraff, Nancy C; Whitney, Susan L; Rubinstein, Elaine N et al. (2006) Use of the physical performance test to assess preclinical disability in subjects with asymptomatic carotid artery disease. Phys Ther 86:541-8
Whitney, Susan L; Sparto, Patrick J; Hodges, Larry F et al. (2006) Responses to a virtual reality grocery store in persons with and without vestibular dysfunction. Cyberpsychol Behav 9:152-6

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