Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG020208-01S1
Application #
6682491
Study Section
Cell Development and Function Integrated Review Group (CDF)
Program Officer
Carrington, Jill L
Project Start
2002-02-01
Project End
2007-01-31
Budget Start
2002-12-15
Budget End
2003-01-31
Support Year
1
Fiscal Year
2003
Total Cost
$31,241
Indirect Cost
Name
Harvard University
Department
Pathology
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115
Hinds, Philip W (2014) A little pRB can lead to big problems. Cancer Discov 4:764-5
Luo, Chi; Sheng, Jinghao; Hu, Miaofen G et al. (2013) Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC. Cancer Res 73:4337-48
Gunduz, Volkan; Kong, Elizabeth; Bryan, Crystal D et al. (2012) Loss of the retinoblastoma tumor suppressor protein in murine calvaria facilitates immortalization of osteoblast-adipocyte bipotent progenitor cells characterized by low expression of N-cadherin. Mol Cell Biol 32:2561-9
Zhang, Weibo; Vazquez, Betsy; Andreeva, Viktoria et al. (2012) Discrete phosphorylated retinoblastoma protein isoform expression in mouse tooth development. J Mol Histol 43:281-8
Huang, Mingqian; Sage, Cyrille; Tang, Yong et al. (2011) Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs. Cell Cycle 10:337-51
Sosa-Garcia, Bernadette; Gunduz, Volkan; Vazquez-Rivera, Viviana et al. (2010) A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation. PLoS One 5:e13954
Mao, Daqin; Hinds, Philip W (2010) p35 is required for CDK5 activation in cellular senescence. J Biol Chem 285:14671-80
Lazebnik, Maria B; Tussie-Luna, Maria Isabel; Hinds, Philip W et al. (2009) Williams-Beuren syndrome-associated transcription factor TFII-I regulates osteogenic marker genes. J Biol Chem 284:36234-9
Gutierrez, Gabriel M; Kong, Elizabeth; Sabbagh, Yves et al. (2008) Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proc Natl Acad Sci U S A 105:18402-7
Wang, Yang; Ray, Subir K; Hinds, Philip W et al. (2007) The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression. Dev Biol 311:478-86

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