Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI011183-23
Application #
2059769
Study Section
Immunobiology Study Section (IMB)
Project Start
1978-04-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
23
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Microbiology/Immun/Virology
Type
Schools of Arts and Sciences
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Melo, Marco E F; Gabaglia, Claudia Raja; Moudgil, Kamal D et al. (2002) Strain-dependent effect of nasal instillation of antigen on the immune response in mice. Isr Med Assoc J 4:902-7
Moudgil, K D; Kim, E; Yun, O J et al. (2001) Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65. J Immunol 166:4237-43
Kang, H K; Mikszta, J A; Deng, H et al. (2000) Processing and reactivity of T cell epitopes containing two cysteine residues from hen egg-white lysozyme (HEL74-90). J Immunol 164:1775-82
Moudgil, K D; Sercarz, E E (2000) The self-directed T cell repertoire: its creation and activation. Rev Immunogenet 2:26-37
Schneider, S C; Ohmen, J; Fosdick, L et al. (2000) Cutting edge: introduction of an endopeptidase cleavage motif into a determinant flanking region of hen egg lysozyme results in enhanced T cell determinant display. J Immunol 165:20-3
Moudgil, K D; Southwood, S; Ametani, A et al. (1999) The self-directed T cell repertoire against mouse lysozyme reflects the influence of the hierarchy of its own determinants and can be engaged by a foreign lysozyme. J Immunol 163:4232-7
Gabaglia, C R; Pedersen, B; Hitt, M et al. (1999) A single intramuscular injection with an adenovirus-expressing IL-12 protects BALB/c mice against Leishmania major infection, while treatment with an IL-4-expressing vector increases disease susceptibility in B10.D2 mice. J Immunol 162:753-60
Moudgil, K D (1998) Diversification of response to hsp65 during the course of autoimmune arthritis is regulatory rather than pathogenic. Immunol Rev 164:175-84
Borghans, J A; De Boer, R J; Sercarz, E et al. (1998) T cell vaccination in experimental autoimmune encephalomyelitis: a mathematical model. J Immunol 161:1087-93
Moudgil, K D; Wang, J; Yeung, V P et al. (1998) Heterogeneity of the T cell response to immunodominant determinants within hen eggwhite lysozyme of individual syngeneic hybrid F1 mice: implications for autoimmunity and infection. J Immunol 161:6046-53

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