Abstract

Dendritic cells have been shown to be potent stimulators of the syngeneic mixed leukocyte reaction. DC are accessory cells for the development of cytotoxic T lymphocytes. Macrophages, including Ia bearing M0, are weak or inactive in these assays.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI013013-09
Application #
3125355
Study Section
Immunobiology Study Section (IMB)
Project Start
1979-04-01
Project End
1985-12-31
Budget Start
1985-01-01
Budget End
1985-12-31
Support Year
9
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
Rockefeller University
Department
Type
Graduate Schools
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

Loschko, Jakob; Rieke, Gereon J; Schreiber, Heidi A et al. (2016) Inducible targeting of cDCs and their subsets in vivo. J Immunol Methods 434:32-8
Loschko, Jakob; Schreiber, Heidi A; Rieke, Gereon J et al. (2016) Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation. J Exp Med 213:517-34
Lee, Jaeyop; Breton, Gaëlle; Oliveira, Thiago Yukio Kikuchi et al. (2015) Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med 212:385-99
Lee, Jaeyop; Breton, Gaëlle; Aljoufi, Arafat et al. (2015) Clonal analysis of human dendritic cell progenitor using a stromal cell culture. J Immunol Methods 425:21-26
Silva-Sánchez, Aarón; Meza-Pérez, Selene; Flores-Langarica, Adriana et al. (2015) ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis. PLoS One 10:e0124828
Breton, Gaëlle; Lee, Jaeyop; Zhou, Yu Jerry et al. (2015) Circulating precursors of human CD1c+ and CD141+ dendritic cells. J Exp Med 212:401-13
Breton, Gaëlle; Lee, Jaeyop; Liu, Kang et al. (2015) Defining human dendritic cell progenitors by multiparametric flow cytometry. Nat Protoc 10:1407-22
Pantel, Austin; Teixeira, Angela; Haddad, Elias et al. (2014) Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation. PLoS Biol 12:e1001759
Mollah, Shamim A; Dobrin, Joseph S; Feder, Rachel E et al. (2014) Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. J Invest Dermatol 134:1265-1275
Anandasabapathy, Niroshana; Feder, Rachel; Mollah, Shamim et al. (2014) Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. J Exp Med 211:1875-91

Showing the most recent 10 out of 132 publications