Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI017416-13
Application #
2060512
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1980-12-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Rydkina, Elena; Silverman, David J; Sahni, Sanjeev K (2005) Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response. Cell Microbiol 7:1519-30
Rydkina, Elena; Sahni, Sanjeev K; Santucci, Lisa A et al. (2004) Selective modulation of antioxidant enzyme activities in host tissues during Rickettsia conorii infection. Microb Pathog 36:293-301
Joshi, Suresh G; Francis, Charles W; Silverman, David J et al. (2004) NF-kappaB activation suppresses host cell apoptosis during Rickettsia rickettsii infection via regulatory effects on intracellular localization or levels of apoptogenic and anti-apoptotic proteins. FEMS Microbiol Lett 234:333-41
Sahni, Sanjeev K; Rydkina, Elena; Joshi, Suresh G et al. (2003) Interactions of Rickettsia rickettsii with endothelial nuclear factor-kappaB in a ""cell-free"" system. Ann N Y Acad Sci 990:635-41
Joshi, Suresh G; Francis, Charles W; Silverman, David J et al. (2003) Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity. Infect Immun 71:4127-36
Eremeeva, Marina E; Klemt, Ryan M; Santucci-Domotor, Lisa A et al. (2003) Genetic analysis of isolates of Rickettsia rickettsii that differ in virulence. Ann N Y Acad Sci 990:717-22
Eremeeva, Marina E; Liang, Zhongxing; Paddock, Christopher et al. (2003) Rickettsia rickettsii infection in the pine vole, Microtus pinetorum: kinetics of infection and quantitation of antioxidant enzyme gene expression by RT-PCR. Ann N Y Acad Sci 990:468-73
Eremeeva, Marina E; Dasch, Gregory A; Silverman, David J (2003) Evaluation of a PCR assay for quantitation of Rickettsia rickettsii and closely related spotted fever group rickettsiae. J Clin Microbiol 41:5466-72
Rydkina, Elena; Sahni, Abha; Silverman, David J et al. (2002) Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression. Infect Immun 70:4045-52
Eremeeva, M E; Dasch, G A; Silverman, D J (2001) Quantitative analyses of variations in the injury of endothelial cells elicited by 11 isolates of Rickettsia rickettsii. Clin Diagn Lab Immunol 8:788-96

Showing the most recent 10 out of 30 publications