Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI017979-13
Application #
2060601
Study Section
Special Emphasis Panel (ZRG5-EI (03))
Project Start
1982-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
Walker, W S (1999) Separate precursor cells for macrophages and microglia in mouse brain: immunophenotypic and immunoregulatory properties of the progeny. J Neuroimmunol 94:127-33
Havenith, C E; Askew, D; Walker, W S (1998) Mouse resident microglia: isolation and characterization of immunoregulatory properties with naive CD4+ and CD8+ T-cells. Glia 22:348-59
Nguyen, V T; Walker, W S; Benveniste, E N (1998) Post-transcriptional inhibition of CD40 gene expression in microglia by transforming growth factor-beta. Eur J Immunol 28:2537-48
Walker, W S; Castrucci, M R; Sangster, M Y et al. (1997) HEL-Flu: an influenza virus containing the hen egg lysozyme epitope recognized by CD4+ T cells from mice transgenic for an alphabeta TCR. J Immunol 159:2563-6
Askew, D; Gatewood, J; Olivas, E et al. (1995) A subset of splenic macrophages process and present native antigen to naive antigen-specific CD4+ T-cells from mice transgenic for an alpha beta T-cell receptor. Cell Immunol 166:62-70
Olivas, E; Chen, B B; Walker, W S (1995) Use of the Pannell-Milstein roller bottle apparatus to produce high concentrations of the CSF-1, the mouse macrophage growth factor. J Immunol Methods 182:73-9
McCormack, J M; Leenen, P J; Walker, W S (1993) Macrophage progenitors from mouse bone marrow and spleen differ in their expression of the Ly-6C differentiation antigen. J Immunol 151:6389-98
McCormack, J M; Askew, D; Walker, W S (1993) Alloantigen presentation by individual clones of mouse splenic macrophages. Selective expression of IL-1 alpha in response to CD8+ T cell-derived IFN-gamma defines the alloantigen-presenting phenotype. J Immunol 151:5218-27
Moore, S C; McCormack, J M; Armendariz, E et al. (1992) Phenotypes and alloantigen-presenting activity of individual clones of microglia derived from the mouse brain. J Neuroimmunol 41:203-14
McCormack, J M; Moore, S C; Gatewood, J W et al. (1992) Mouse splenic macrophage cell lines with different antigen-presenting activities for CD4+ helper T cell subsets and allogeneic CD8+ T cells. Cell Immunol 145:359-71

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