Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI018641-14
Application #
2060748
Study Section
Virology Study Section (VR)
Project Start
1982-09-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Institute for Cancer Research
Department
Type
DUNS #
872612445
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Cai, Dawei; Mills, Courtney; Yu, Wenquan et al. (2012) Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation. Antimicrob Agents Chemother 56:4277-88
Mason, William S; Liu, Chen; Aldrich, Carol E et al. (2010) Clonal expansion of normal-appearing human hepatocytes during chronic hepatitis B virus infection. J Virol 84:8308-15
Mason, William S; Low, Huey-Chi; Xu, Chunxiao et al. (2009) Detection of clonally expanded hepatocytes in chimpanzees with chronic hepatitis B virus infection. J Virol 83:8396-408
Mason, William S; Xu, Chunxiao; Low, Huey Chi et al. (2009) The amount of hepatocyte turnover that occurred during resolution of transient hepadnavirus infections was lower when virus replication was inhibited with entecavir. J Virol 83:1778-89
Mason, W S; Litwin, S; Xu, C et al. (2007) Hepatocyte turnover in transient and chronic hepadnavirus infections. J Viral Hepat 14 Suppl 1:22-8
Xu, Chunxiao; Yamamoto, Toshiki; Zhou, Tianlun et al. (2007) The liver of woodchucks chronically infected with the woodchuck hepatitis virus contains foci of virus core antigen-negative hepatocytes with both altered and normal morphology. Virology 359:283-94
Guo, Haitao; Mason, William S; Aldrich, Carol E et al. (2005) Identification and characterization of avihepadnaviruses isolated from exotic anseriformes maintained in captivity. J Virol 79:2729-42
Yamamoto, Toshiki; Litwin, Samuel; Zhou, Tianlun et al. (2002) Mutations of the woodchuck hepatitis virus polymerase gene that confer resistance to lamivudine and 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil. J Virol 76:1213-23
Zhu, Y; Yamamoto, T; Cullen, J et al. (2001) Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis. J Virol 75:311-22
Zhou, T; Saputelli, J; Aldrich, C E et al. (1999) Emergence of drug-resistant populations of woodchuck hepatitis virus in woodchucks treated with the antiviral nucleoside lamivudine. Antimicrob Agents Chemother 43:1947-54

Showing the most recent 10 out of 45 publications