Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020323-13
Application #
2061176
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1983-08-01
Project End
1997-03-31
Budget Start
1995-06-01
Budget End
1997-03-31
Support Year
13
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Ravindran, Sriram; Grys, Thomas E; Welch, Rodney A et al. (2004) Inhibition of plasma kallikrein by C1-inhibitor: role of endothelial cells and the amino-terminal domain of C1-inhibitor. Thromb Haemost 92:1277-83
Lathem, Wyndham W; Bergsbaken, Tessa; Welch, Rodney A (2004) Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by Escherichia coli O157:H7. J Exp Med 199:1077-87
Lathem, Wyndham W; Bergsbaken, Tessa; Witowski, Sarah E et al. (2003) Acquisition of stcE, a C1 esterase inhibitor-specific metalloprotease, during the evolution of Escherichia coli O157:H7. J Infect Dis 187:1907-14
Lathem, Wyndham W; Grys, Thomas E; Witowski, Sarah E et al. (2002) StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor. Mol Microbiol 45:277-88
Lim, K B; Walker, C R; Guo, L et al. (2000) Escherichia coli alpha-hemolysin (HlyA) is heterogeneously acylated in vivo with 14-, 15-, and 17-carbon fatty acids. J Biol Chem 275:36698-702
Serwecinska, L; Pytlos, M; Lukomski, S et al. (1997) The simultaneous production of both Hly- and Hpm-like hemolysins is characteristic of the Proteus penneri species. J Basic Microbiol 37:361-70
Leeds, J A; Welch, R A (1997) Enhancing transcription through the Escherichia coli hemolysin operon, hlyCABD: RfaH and upstream JUMPStart DNA sequences function together via a postinitiation mechanism. J Bacteriol 179:3519-27
Bauer, M E; Welch, R A (1997) Pleiotropic effects of a mutation in rfaC on Escherichia coli hemolysin. Infect Immun 65:2218-24
Moayeri, M; Welch, R A (1997) Prelytic and lytic conformations of erythrocyte-associated Escherichia coli hemolysin. Infect Immun 65:2233-9
Leeds, J A; Welch, R A (1996) RfaH enhances elongation of Escherichia coli hlyCABD mRNA. J Bacteriol 178:1850-7

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