Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020451-12
Application #
2061221
Study Section
Experimental Immunology Study Section (EI)
Project Start
1983-08-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Chlewicki, Lukasz K; Velikovsky, C Alejandro; Balakrishnan, Vamsi et al. (2008) Molecular basis of the dual functions of 2B4 (CD244). J Immunol 180:8159-67
Lee, Kyung-Mi; Forman, John P; McNerney, Megan E et al. (2006) Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions. Blood 107:3181-8
McNerney, M E; Lee, K-M; Zhou, P et al. (2006) Role of natural killer cell subsets in cardiac allograft rejection. Am J Transplant 6:505-13
McNerney, Megan E; Guzior, Dustin; Kumar, Vinay (2005) 2B4 (CD244)-CD48 interactions provide a novel MHC class I-independent system for NK-cell self-tolerance in mice. Blood 106:1337-40
McNerney, Megan E; Lee, Kyung-Mi; Kumar, Vinay (2005) 2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells. Mol Immunol 42:489-94
Lian, Rebecca H; Chin, Robert K; Nemeth, Hajnalka E et al. (2004) A role for lymphotoxin in the acquisition of Ly49 receptors during NK cell development. Eur J Immunol 34:2699-707
Lee, Kyung-Mi; McNerney, Megan E; Stepp, Susan E et al. (2004) 2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells. J Exp Med 199:1245-54
Lee, Kyung-Mi; Bhawan, Sadhna; Majima, Takashi et al. (2003) Cutting edge: the NK cell receptor 2B4 augments antigen-specific T cell cytotoxicity through CD48 ligation on neighboring T cells. J Immunol 170:4881-5
Kawamura, Toshihiko; Koka, Rima; Ma, Averil et al. (2003) Differential roles for IL-15R alpha-chain in NK cell development and Ly-49 induction. J Immunol 171:5085-90
Catalina, Fernando; Milewich, Leon; Kumar, Vinay et al. (2003) Dietary dehydroepiandrosterone inhibits bone marrow and leukemia cell transplants: role of food restriction. Exp Biol Med (Maywood) 228:1303-20

Showing the most recent 10 out of 44 publications