Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI020519-13S1
Application #
2327149
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1983-05-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Hinman, Rochelle M; Smith, Mia J; Cambier, John C (2014) B cells and type 1 diabetes ...in mice and men. Immunol Lett 160:128-32
Yarkoni, Yuval; Getahun, Andrew; Cambier, John C (2010) Molecular underpinning of B-cell anergy. Immunol Rev 237:249-63
Waterman, Paul M; Cambier, John C (2010) The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms. FEBS Lett 584:4878-82
Getahun, Andrew; O'Neill, Shannon K; Cambier, John C (2009) Establishing anergy as a bona fide in vivo mechanism of B cell tolerance. J Immunol 183:5439-41
O'Neill, Shannon K; Liu, Edwin; Cambier, John C (2009) Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes 16:293-8
Jin, Lei; Waterman, Paul M; Jonscher, Karen R et al. (2008) MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals. Mol Cell Biol 28:5014-26
Jin, Lei; Stolpa, John C; Young, Ryan M et al. (2008) MHC class II structural requirements for the association with Igalpha/beta, and signaling of calcium mobilization and cell death. Immunol Lett 116:184-94
Gauld, Stephen B; Benschop, Robert J; Merrell, Kevin T et al. (2005) Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling. Nat Immunol 6:1160-7
Jordan, Michael B; Mills, David M; Kappler, John et al. (2004) Promotion of B cell immune responses via an alum-induced myeloid cell population. Science 304:1808-10
Mills, David M; Stolpa, John C; Cambier, John C (2004) Cognate B cell signaling via MHC class II: differential regulation of B cell antigen receptor and MHC class II/Ig-alpha beta signaling by CD22. J Immunol 172:195-201

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