Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI021487-11S1
Application #
2061536
Study Section
Immunobiology Study Section (IMB)
Project Start
1984-01-01
Project End
1998-12-31
Budget Start
1994-01-01
Budget End
1994-12-31
Support Year
11
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Ishimaru, Naozumi; Kishimoto, Hidehiro; Hayashi, Yoshio et al. (2006) Regulation of naive T cell function by the NF-kappaB2 pathway. Nat Immunol 7:763-72
Kovar, Marek; Boyman, Onur; Shen, Xuefei et al. (2006) Direct stimulation of T cells by membrane vesicles from antigen-presenting cells. Proc Natl Acad Sci U S A 103:11671-6
Sprent, Jonathan (2005) Direct stimulation of naive T cells by antigen-presenting cell vesicles. Blood Cells Mol Dis 35:17-20
Lenz, Derek C; Kurz, Sabine K; Lemmens, Edward et al. (2004) IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory. Proc Natl Acad Sci U S A 101:9357-62
Hwang, Inkyu; Shen, Xuefei; Sprent, Jonathan (2003) Direct stimulation of naive T cells by membrane vesicles from antigen-presenting cells: distinct roles for CD54 and B7 molecules. Proc Natl Acad Sci U S A 100:6670-5
Sprent, Jonathan; Surh, Charles D (2003) Cytokines and T cell homeostasis. Immunol Lett 85:145-9
Sprent, Jonathan (2003) Turnover of memory-phenotype CD8+ T cells. Microbes Infect 5:227-31
Tan, Joyce T; Ernst, Bettina; Kieper, William C et al. (2002) Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med 195:1523-32
Zhang, Xiaohong; Fujii, Hideki; Kishimoto, Hidehiro et al. (2002) Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells. J Exp Med 195:283-93
Judge, Adam D; Zhang, Xiaohong; Fujii, Hideki et al. (2002) Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med 196:935-46

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