Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI021758-12
Application #
2061610
Study Section
Virology Study Section (VR)
Project Start
1984-12-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Greseth, Matthew D; Czarnecki, Maciej W; Bluma, Matthew S et al. (2018) Isolation and Characterization of v?I3 Confirm that Vaccinia Virus SSB Plays an Essential Role in Viral Replication. J Virol 92:
Czarnecki, Maciej W; Traktman, Paula (2017) The vaccinia virus DNA polymerase and its processivity factor. Virus Res 234:193-206
Boyle, Kathleen A; Greseth, Matthew D; Traktman, Paula (2015) Genetic Confirmation that the H5 Protein Is Required for Vaccinia Virus DNA Replication. J Virol 89:6312-27
Greseth, Matthew D; Boyle, Kathleen A; Bluma, Matthew S et al. (2012) Molecular genetic and biochemical characterization of the vaccinia virus I3 protein, the replicative single-stranded DNA binding protein. J Virol 86:6197-209
Boyle, Kathleen A; Stanitsa, Eleni S; Greseth, Matthew D et al. (2011) Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme. J Biol Chem 286:24702-13
Wiebe, Matthew S; Traktman, Paula (2007) Poxviral B1 kinase overcomes barrier to autointegration factor, a host defense against virus replication. Cell Host Microbe 1:187-97
Boyle, Kathleen A; Arps, Lisa; Traktman, Paula (2007) Biochemical and genetic analysis of the vaccinia virus d5 protein: Multimerization-dependent ATPase activity is required to support viral DNA replication. J Virol 81:844-59
Stanitsa, Eleni S; Arps, Lisa; Traktman, Paula (2006) Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase. J Biol Chem 281:3439-51
Boyle, Kathleen A; Traktman, Paula (2004) Members of a novel family of mammalian protein kinases complement the DNA-negative phenotype of a vaccinia virus ts mutant defective in the B1 kinase. J Virol 78:1992-2005
Traktman, Paula; Boyle, Kathleen (2004) Methods for analysis of poxvirus DNA replication. Methods Mol Biol 269:169-86

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