Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI022039-11A1
Application #
2061690
Study Section
Special Emphasis Panel (ZRG2-ALY (01))
Project Start
1985-09-30
Project End
2001-06-30
Budget Start
1996-07-15
Budget End
1997-06-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Biology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Illing, Patricia T; Pymm, Phillip; Croft, Nathan P et al. (2018) HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun 9:4693
Pugh, Jason L; Nemat-Gorgani, Neda; Norman, Paul J et al. (2018) Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage. J Immunol 200:1146-1158
Djaoud, Zakia; Guethlein, Lisbeth A; Horowitz, Amir et al. (2017) Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and ?? T cells. J Exp Med 214:1827-1841
Hilton, Hugo G; Parham, Peter (2017) Missing or altered self: human NK cell receptors that recognize HLA-C. Immunogenetics 69:567-579
Hilton, Hugo G; Blokhuis, Jeroen H; Guethlein, Lisbeth A et al. (2017) Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C. J Immunol 198:1961-1973
Blokhuis, Jeroen H; Hilton, Hugo G; Guethlein, Lisbeth A et al. (2017) KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans. Immun Inflamm Dis 5:461-468
Hilton, Hugo G; McMurtrey, Curtis P; Han, Alex S et al. (2017) The Intergenic Recombinant HLA-B?46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands. Cell Rep 19:1394-1405
Horowitz, Amir; Djaoud, Zakia; Nemat-Gorgani, Neda et al. (2016) Class I HLA haplotypes form two schools that educate NK cells in different ways. Sci Immunol 1:
Hilton, Hugo G; Norman, Paul J; Nemat-Gorgani, Neda et al. (2015) Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population. PLoS Genet 11:e1005439
Hilton, Hugo G; Moesta, Achim K; Guethlein, Lisbeth A et al. (2015) The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay. J Immunol Methods 425:79-87

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