Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI022532-12
Application #
2061872
Study Section
Immunobiology Study Section (IMB)
Project Start
1985-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Harvard University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Satoskar, A R; Bozza, M; Rodriguez Sosa, M et al. (2001) Migration-inhibitory factor gene-deficient mice are susceptible to cutaneous Leishmania major infection. Infect Immun 69:906-11
Satoskar, A R; Rodig, S; Telford 3rd, S R et al. (2000) IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic immunopathology. Eur J Immunol 30:834-9
Ochi, H; Hirani, W M; Yuan, Q et al. (1999) T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro. J Exp Med 190:267-80
Satoskar, A R; Stamm, L M; Zhang, X et al. (1999) Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection. J Immunol 162:6747-54
Stamm, L M; Satoskar, A A; Ghosh, S K et al. (1999) STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis. Eur J Immunol 29:2524-9
Bozza, M; Satoskar, A R; Lin, G et al. (1999) Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis. J Exp Med 189:341-6
Soares, M B; Titus, R G; Shoemaker, C B et al. (1998) The vasoactive peptide maxadilan from sand fly saliva inhibits TNF-alpha and induces IL-6 by mouse macrophages through interaction with the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor. J Immunol 160:1811-6
Bozza, M; Soares, M B; Bozza, P T et al. (1998) The PACAP-type I receptor agonist maxadilan from sand fly saliva protects mice against lethal endotoxemia by a mechanism partially dependent on IL-10. Eur J Immunol 28:3120-7
Stamm, L M; Raisanen-Sokolowski, A; Okano, M et al. (1998) Mice with STAT6-targeted gene disruption develop a Th1 response and control cutaneous leishmaniasis. J Immunol 161:6180-8
Soares, M B; David, J R; Titus, R G (1997) An in vitro model for infection with Leishmania major that mimics the immune response in mice. Infect Immun 65:2837-45

Showing the most recent 10 out of 45 publications