Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI023455-08A4
Application #
2062200
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1985-09-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Providence Portland Medical Center
Department
Type
DUNS #
City
Portland
State
OR
Country
United States
Zip Code
97213
Barry, Ronald A; Archie Bouwer, H G; Clark, Tina R et al. (2003) Protection of interferon-gamma knockout mice against Listeria monocytogenes challenge following intramuscular immunization with DNA vaccines encoding listeriolysin O. Vaccine 21:2122-32
Bouwer, H G; Barry, R A; Hinrichs, D J (2001) Lack of expansion of major histocompatibility complex class Ib-restricted effector cells following recovery from secondary infection with the intracellular pathogen Listeria monocytogenes. Infect Immun 69:2286-92
Cornell, K A; Bouwer, H G; Hinrichs, D J et al. (1999) Genetic immunization of mice against Listeria monocytogenes using plasmid DNA encoding listeriolysin O. J Immunol 163:322-9
Bouwer, H G; Shen, H; Fan, X et al. (1999) Existing antilisterial immunity does not inhibit the development of a Listeria monocytogenes-specific primary cytotoxic T-lymphocyte response. Infect Immun 67:253-8
Bouwer, H G; Bai, A; Forman, J et al. (1998) Listeria monocytogenes-infected hepatocytes are targets of major histocompatibility complex class Ib-restricted antilisterial cytotoxic T lymphocytes. Infect Immun 66:2814-7
Bouwer, H G; Barry, R A; Hinrichs, D J (1997) Acquired immunity to an intracellular pathogen: immunologic recognition of L. monocytogenes-infected cells. Immunol Rev 158:137-46
Bouwer, H G; Seaman, M S; Forman, J et al. (1997) MHC class Ib-restricted cells contribute to antilisterial immunity: evidence for Qa-1b as a key restricting element for Listeria-specific CTLs. J Immunol 159:2795-801
Bouwer, H G; Hinrichs, D J (1996) Cytotoxic-T-lymphocyte responses to epitopes of listeriolysin O and p60 following infection with Listeria monocytogenes. Infect Immun 64:2515-22
Bouwer, H G; Moors, M; Hinrichs, D J (1996) Elimination of the listeriolysin O-directed immune response by conservative alteration of the immunodominant listeriolysin O amino acid 91 to 99 epitope. Infect Immun 64:3728-35
Bouwer, H G; Gibbins, B L; Jones, S et al. (1994) Antilisterial immunity includes specificity to listeriolysin O (LLO) and non-LLO-derived determinants. Infect Immun 62:1039-45

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