Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI023884-10
Application #
2062372
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1986-07-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Public Health Research Institute
Department
Type
DUNS #
City
Newark
State
NY
Country
United States
Zip Code
Pinter, A; Honnen, W J; Kayman, S C et al. (1998) Potent neutralization of primary HIV-1 isolates by antibodies directed against epitopes present in the V1/V2 domain of HIV-1 gp120. Vaccine 16:1803-11
Pincus, S H; Cole, R L; Watson-McKown, R et al. (1998) Immunologic cross-reaction between HIV type 1 p17 and Mycoplasma hyorhinis variable lipoprotein. AIDS Res Hum Retroviruses 14:419-25
Pincus, S H; Messer, K G; Cole, R et al. (1997) Vaccine-specific antibody responses induced by HIV-1 envelope subunit vaccines. J Immunol 158:3511-20
Pinter, A; Kopelman, R; Li, Z et al. (1997) Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol-disulfide exchange enzymes. J Virol 71:8073-7
Li, Z; Pinter, A; Kayman, S C (1997) The critical N-linked glycan of murine leukemia virus envelope protein promotes both folding of the C-terminal domains of the precursor polyprotein and stability of the postcleavage envelope complex. J Virol 71:7012-9
Alsmadi, O; Herz, R; Murphy, E et al. (1997) A novel antibody-dependent cellular cytotoxicity epitope in gp120 is identified by two monoclonal antibodies isolated from a long-term survivor of human immunodeficiency virus type 1 infection. J Virol 71:925-33
Vijh-Warrier, S; Pinter, A; Honnen, W J et al. (1996) Synergistic neutralization of human immunodeficiency virus type 1 by a chimpanzee monoclonal antibody against the V2 domain of gp120 in combination with monoclonal antibodies against the V3 loop and the CD4-binding site. J Virol 70:4466-73
Demaria, S; Tilley, S A; Pinter, A et al. (1995) Bathophenanthroline disulfonate and soluble CD4 as probes for early events of HIV type 1 entry. AIDS Res Hum Retroviruses 11:127-39
Wu, Z; Kayman, S C; Honnen, W et al. (1995) Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain. J Virol 69:2271-8
Warrier, S V; Pinter, A; Honnen, W J et al. (1994) A novel, glycan-dependent epitope in the V2 domain of human immunodeficiency virus type 1 gp120 is recognized by a highly potent, neutralizing chimpanzee monoclonal antibody. J Virol 68:4636-42

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