Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI023970-10
Application #
2062407
Study Section
Experimental Virology Study Section (EVR)
Project Start
1986-08-01
Project End
1997-05-31
Budget Start
1995-06-01
Budget End
1997-05-31
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Zuercher, Adrian W (2003) Upper respiratory tract immunity. Viral Immunol 16:279-89
Zuercher, Adrian W; Coffin, Susan E; Thurnheer, M Christine et al. (2002) Nasal-associated lymphoid tissue is a mucosal inductive site for virus-specific humoral and cellular immune responses. J Immunol 168:1796-803
Zuercher, Adrian W; Jiang, Han-Qing; Thurnheer, M Christine et al. (2002) Distinct mechanisms for cross-protection of the upper versus lower respiratory tract through intestinal priming. J Immunol 169:3920-5
Zuercher, Adrian W; Cebra, John J (2002) Structural and functional differences between putative mucosal inductive sites of the rat. Eur J Immunol 32:3191-6
Kushnir, N; Bos, N A; Zuercher, A W et al. (2001) B2 but not B1 cells can contribute to CD4+ T-cell-mediated clearance of rotavirus in SCID mice. J Virol 75:5482-90
Cebra, J J (1999) Influences of microbiota on intestinal immune system development. Am J Clin Nutr 69:1046S-1051S
Periwal, S B; Cebra, J J (1999) Respiratory mucosal immunization with reovirus serotype 1/L stimulates virus-specific humoral and cellular immune responses, including double-positive (CD4(+)/CD8(+)) T cells. J Virol 73:7633-40
Cebra, J J; Periwal, S B; Lee, G et al. (1998) Development and maintenance of the gut-associated lymphoid tissue (GALT): the roles of enteric bacteria and viruses. Dev Immunol 6:13-8
Major, A S; Rubin, D H; Cuff, C F (1998) Mucosal immunity to reovirus infection. Curr Top Microbiol Immunol 233:163-77
Periwal, S B; Speaker, T J; Cebra, J J (1997) Orally administered microencapsulated reovirus can bypass suckled, neutralizing maternal antibody that inhibits active immunization of neonates. J Virol 71:2844-50

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