Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI025011-05
Application #
2062844
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1987-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Mueller-Ortiz, Stacey L; Calame, Daniel G; Shenoi, Nancy et al. (2017) The Complement Anaphylatoxins C5a and C3a Suppress IFN-? Production in Response to Listeria monocytogenes by Inhibition of the Cyclic Dinucleotide-Activated Cytosolic Surveillance Pathway. J Immunol 198:3237-3244
Calame, Daniel G; Mueller-Ortiz, Stacey L; Wetsel, Rick A (2016) Innate and adaptive immunologic functions of complement in the host response to Listeria monocytogenes infection. Immunobiology 221:1407-1417
Hu, Xianzhen; Wetsel, Rick A; Ramos, Theresa N et al. (2014) Carboxypeptidase N-deficient mice present with polymorphic disease phenotypes on induction of experimental autoimmune encephalomyelitis. Immunobiology 219:104-8
Calame, Daniel G; Mueller-Ortiz, Stacey L; Morales, John E et al. (2014) The C5a anaphylatoxin receptor (C5aR1) protects against Listeria monocytogenes infection by inhibiting type 1 IFN expression. J Immunol 193:5099-107
Mueller-Ortiz, Stacey L; Morales, John E; Wetsel, Rick A (2014) The receptor for the complement C3a anaphylatoxin (C3aR) provides host protection against Listeria monocytogenes-induced apoptosis. J Immunol 193:1278-89
Dutow, Pavel; Fehlhaber, Beate; Bode, Jenny et al. (2014) The complement C3a receptor is critical in defense against Chlamydia psittaci in mouse lung infection and required for antibody and optimal T cell response. J Infect Dis 209:1269-78
Darley, M M; Ramos, T N; Wetsel, R A et al. (2012) Deletion of carboxypeptidase N delays onset of experimental cerebral malaria. Parasite Immunol 34:444-7
Lim, Hoyong; Kim, Young Uk; Drouin, Scott M et al. (2012) Negative regulation of pulmonary Th17 responses by C3a anaphylatoxin during allergic inflammation in mice. PLoS One 7:e52666
Wang, Dachun; Morales, John E; Calame, Daniel G et al. (2010) Transplantation of human embryonic stem cell-derived alveolar epithelial type II cells abrogates acute lung injury in mice. Mol Ther 18:625-34
Mueller-Ortiz, Stacey L; Wang, Dachun; Morales, John E et al. (2009) Targeted disruption of the gene encoding the murine small subunit of carboxypeptidase N (CPN1) causes susceptibility to C5a anaphylatoxin-mediated shock. J Immunol 182:6533-9

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