Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
9R01AI026449-08
Application #
3140191
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1988-01-01
Project End
1992-12-31
Budget Start
1988-01-01
Budget End
1988-12-31
Support Year
8
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Lu, Ling; Lamm, Michael E; Li, Hongmin et al. (2003) The human polymeric immunoglobulin receptor binds to Streptococcus pneumoniae via domains 3 and 4. J Biol Chem 278:48178-87
Lamm, Michael E; Phillips-Quagliata, Julia M (2002) Origin and homing of intestinal IgA antibody-secreting cells. J Exp Med 195:F5-8
Yan, Huimin; Lamm, Michael E; Bjorling, Ewa et al. (2002) Multiple functions of immunoglobulin A in mucosal defense against viruses: an in vitro measles virus model. J Virol 76:10972-9
Robinson, J K; Blanchard, T G; Levine, A D et al. (2001) A mucosal IgA-mediated excretory immune system in vivo. J Immunol 166:3688-92
Chintalacharuvu, S R; Nagy, N U; Sigmund, N et al. (2001) T cell cytokines determine the severity of experimental IgA nephropathy by regulating IgA glycosylation. Clin Exp Immunol 126:326-33
Huang, Y T; Miller, C J; Wong, V et al. (1999) Replication and budding of simian immunodeficiency virus in polarized epithelial cells. Virology 257:24-34
Lamm, M E (1998) Current concepts in mucosal immunity. IV. How epithelial transport of IgA antibodies relates to host defense. Am J Physiol 274:G614-7
Lamm, M E (1997) Interaction of antigens and antibodies at mucosal surfaces. Annu Rev Microbiol 51:311-40
Kaetzel, C S; Blanch, V J; Hempen, P M et al. (1997) The polymeric immunoglobulin receptor: structure and synthesis. Biochem Soc Trans 25:475-80
Piskurich, J F; Youngman, K R; Phillips, K M et al. (1997) Transcriptional regulation of the human polymeric immunoglobulin receptor gene by interferon-gamma. Mol Immunol 34:75-91

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