Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI026926-02
Application #
3140985
Study Section
(SSS)
Project Start
1988-09-30
Project End
1991-08-31
Budget Start
1989-09-01
Budget End
1990-08-31
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Roger Williams Hospital
Department
Type
DUNS #
City
Providence
State
RI
Country
United States
Zip Code
02908
Cavacini, Lisa A; Duval, Mark; Patil, Ajay et al. (2005) Dichotomy in cross-clade reactivity and neutralization by HIV-1 sera: Implications for active and passive immunotherapy. J Med Virol 76:146-52
Wilkinson, Royce A; Piscitelli, Chayne; Teintze, Martin et al. (2005) Structure of the Fab fragment of F105, a broadly reactive anti-human immunodeficiency virus (HIV) antibody that recognizes the CD4 binding site of HIV type 1 gp120. J Virol 79:13060-9
Cavacini, Lisa; Duval, Mark; Song, Leslie et al. (2003) Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base. AIDS 17:685-9
Liu, Fangbing; Bergami, Pablo Lopez; Duval, Mark et al. (2003) Expression and functional activity of isotype and subclass switched human monoclonal antibody reactive with the base of the V3 loop of HIV-1 gp120. AIDS Res Hum Retroviruses 19:597-607
Cavacini, Lisa A; Kuhrt, David; Duval, Mark et al. (2003) Binding and neutralization activity of human IgG1 and IgG3 from serum of HIV-infected individuals. AIDS Res Hum Retroviruses 19:785-92
Hofmann-Lehmann, R; Vlasak, J; Rasmussen, R A et al. (2002) Postnatal pre- and postexposure passive immunization strategies: protection of neonatal macaques against oral simian-human immunodeficiency virus challenge. J Med Primatol 31:109-19
Cavacini, Lisa A; Duval, Mark; Robinson, James et al. (2002) Interactions of human antibodies, epitope exposure, antibody binding and neutralization of primary isolate HIV-1 virions. AIDS 16:2409-17
Hofmann-Lehmann, R; Rasmussen, R A; Vlasak, J et al. (2001) Passive immunization against oral AIDS virus transmission: an approach to prevent mother-to-infant HIV-1 transmission? J Med Primatol 30:190-6
Ruprecht, R M; Hofmann-Lehmann, R; Smith-Franklin, B A et al. (2001) Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies. Transfus Clin Biol 8:350-8
Hofmann-Lehmann, R; Vlasak, J; Rasmussen, R A et al. (2001) Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. J Virol 75:7470-80

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