Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI027744-03
Application #
3141973
Study Section
Special Emphasis Panel (ARR (V1))
Project Start
1988-11-01
Project End
1992-10-31
Budget Start
1990-11-01
Budget End
1991-10-31
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Purdue University
Department
Type
Schools of Arts and Sciences
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Thiviyanathan, Varatharasa; Gorenstein, David G (2012) Aptamers and the next generation of diagnostic reagents. Proteomics Clin Appl 6:563-73
Mann, Aman P; Bhavane, Rohan C; Somasunderam, Anoma et al. (2011) Thioaptamer conjugated liposomes for tumor vasculature targeting. Oncotarget 2:298-304
Yang, Xianbin; Li, Na; Gorenstein, David G (2011) Strategies for the discovery of therapeutic aptamers. Expert Opin Drug Discov 6:75-87
Kang, Jonghoon; Lee, Myung Soog; Copland 3rd, John A et al. (2008) Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-beta1 protein. Bioorg Med Chem Lett 18:1835-9
Fennewald, Susan M; Scott, Erin P; Zhang, Lihong et al. (2007) Thioaptamer decoy targeting of AP-1 proteins influences cytokine expression and the outcome of arenavirus infections. J Gen Virol 88:981-90
Kang, Jonghoon; Lee, Myung Soog; Watowich, Stanley J et al. (2007) Combinatorial selection of a RNA thioaptamer that binds to Venezuelan equine encephalitis virus capsid protein. FEBS Lett 581:2497-502
Kang, Jonghoon; Lee, Myung Soog; Gorenstein, David G (2007) Magnesium ion is an effective inhibitor of the binding of Escherichia coli to heparin. J Microbiol Methods 71:340-2
Kang, Jonghoon; Lee, Myung Soog; Gorenstein, David G (2007) Application of RNase in the purification of RNA-binding proteins. Anal Biochem 365:147-8
Kang, Jonghoon; Lee, Myung Soog; Gorenstein, David G (2007) Characterization of heparin-living bacteria interactions by chemiluminescence electrophoretic mobility shift assay. Anal Biochem 363:312-4
Bowick, Gavin C; Fennewald, Susan M; Elsom, Barry L et al. (2006) Differential signaling networks induced by mild and lethal hemorrhagic fever virus infections. J Virol 80:10248-52

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