Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029135-09
Application #
2064835
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1989-09-30
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Biochemistry
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
D'Orso, Iván; Jang, Gwendolyn M; Pastuszak, Alexander W et al. (2012) Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA. Mol Cell Biol 32:4780-93
Nakamura, Robert L; Landt, Stephen G; Mai, Emily et al. (2012) A cell-based method for screening RNA-protein interactions: identification of constitutive transport element-interacting proteins. PLoS One 7:e48194
D'Orso, Iván; Frankel, Alan D (2010) HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear. Viruses 2:2226-2234
D'Orso, Iván; Frankel, Alan D (2010) RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation. Nat Struct Mol Biol 17:815-21
D'Orso, Iván; Frankel, Alan D (2009) Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex. Proc Natl Acad Sci U S A 106:3101-6
D'Orso, Ivan; Grunwell, Jocelyn R; Nakamura, Robert L et al. (2008) Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes. J Virol 82:9492-504
Landt, Stephen G; Tipton, Alicia R; Frankel, Alan D (2005) Localized influence of 2'-hydroxyl groups and helix geometry on protein recognition in the RNA major groove. Biochemistry 44:6547-58
Calabro, Valerie; Daugherty, Matthew D; Frankel, Alan D (2005) A single intermolecular contact mediates intramolecular stabilization of both RNA and protein. Proc Natl Acad Sci U S A 102:6849-54
Xie, Baode; Calabro, Valerie; Wainberg, Mark A et al. (2004) Selection of TAR RNA-binding chameleon peptides by using a retroviral replication system. J Virol 78:1456-63
Das, Chandreyee; Edgcomb, Stephen P; Peteranderl, Ralph et al. (2004) Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1. Virology 318:306-17

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