Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029690-07
Application #
2065163
Study Section
Experimental Immunology Study Section (EI)
Project Start
1990-04-01
Project End
1997-12-31
Budget Start
1996-04-01
Budget End
1997-12-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Aziz, Monowar; Ode, Yasumasa; Zhou, Mian et al. (2018) B-1a cells protect mice from sepsis-induced acute lung injury. Mol Med 24:26
Aziz, Monowar; Holodick, Nichol E; Rothstein, Thomas L et al. (2017) B-1a Cells Protect Mice from Sepsis: Critical Role of CREB. J Immunol 199:750-760
Olofsson, Peder S; Steinberg, Benjamin E; Sobbi, Roozbeh et al. (2016) Blood pressure regulation by CD4(+) lymphocytes expressing choline acetyltransferase. Nat Biotechnol 34:1066-1071
Rothstein, Thomas L (2016) Natural Antibodies as Rheostats for Susceptibility to Chronic Diseases in the Aged. Front Immunol 7:127
Kramer, Jill M; Holodick, Nichol E; Vizconde, Teresa C et al. (2016) Analysis of IgM antibody production and repertoire in a mouse model of Sjögren's syndrome. J Leukoc Biol 99:321-31
Quách, Tâm D; Hopkins, Thomas J; Holodick, Nichol E et al. (2016) Human B-1 and B-2 B Cells Develop from Lin-CD34+CD38lo Stem Cells. J Immunol 197:3950-3958
Sharma, Arjun; Kiripolsky, Jeremy; Klimatcheva, Ekaterina et al. (2016) Early BAFF receptor blockade mitigates murine Sjögren's syndrome: Concomitant targeting of CXCL13 and the BAFF receptor prevents salivary hypofunction. Clin Immunol 164:85-94
Guo, Benchang; Rothstein, Thomas L (2016) RasGRP1 Is an Essential Signaling Molecule for Development of B1a Cells with Autoantigen Receptors. J Immunol 196:2583-90
Guo, Benchang; Zhang, Lu; Chiorazzi, Nicholas et al. (2016) IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. Blood 128:553-62
Holodick, Nichol E; Vizconde, Teresa; Hopkins, Thomas J et al. (2016) Age-Related Decline in Natural IgM Function: Diversification and Selection of the B-1a Cell Pool with Age. J Immunol 196:4348-57

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