Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI030537-04A2
Application #
2065691
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1991-09-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Simoes-Barbosa, Augusto; Chakrabarti, Kausik; Pearson, Michael et al. (2012) Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis. RNA 18:1656-65
Smith, Alias J; Chudnovsky, Lorissa; Simoes-Barbosa, Augusto et al. (2011) Novel core promoter elements and a cognate transcription factor in the divergent unicellular eukaryote Trichomonas vaginalis. Mol Cell Biol 31:1444-58
Smith, Alias; Johnson, Patricia (2011) Gene expression in the unicellular eukaryote Trichomonas vaginalis. Res Microbiol 162:646-54
Simoes-Barbosa, Augusto; Hirt, Robert P; Johnson, Patricia J (2010) A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis. PLoS Pathog 6:e1000999
Simoes-Barbosa, Augusto; Louly, Camila; Franco, Octavio L et al. (2008) The divergent eukaryote Trichomonas vaginalis has an m7G cap methyltransferase capable of a single N2 methylation. Nucleic Acids Res 36:6848-58
Simoes-Barbosa, Augusto; Meloni, Dionigia; Wohlschlegel, James A et al. (2008) Spliceosomal snRNAs in the unicellular eukaryote Trichomonas vaginalis are structurally conserved but lack a 5'-cap structure. RNA 14:1617-31
Lau, Audrey O T; Smith, Alias J; Brown, Mark T et al. (2006) Trichomonas vaginalis initiator binding protein (IBP39) and RNA polymerase II large subunit carboxy terminal domain interaction. Mol Biochem Parasitol 150:56-62
Vanacova, Stepanka; Yan, Weihong; Carlton, Jane M et al. (2005) Spliceosomal introns in the deep-branching eukaryote Trichomonas vaginalis. Proc Natl Acad Sci U S A 102:4430-5
Land, Kirkwood M; Delgadillo-Correa, Maria G; Tachezy, Jan et al. (2004) Targeted gene replacement of a ferredoxin gene in Trichomonas vaginalis does not lead to metronidazole resistance. Mol Microbiol 51:115-22
Schumacher, Maria A; Lau, Audrey O T; Johnson, Patricia J (2003) Structural basis of core promoter recognition in a primitive eukaryote. Cell 115:413-24

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