Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI031209-05
Application #
2066200
Study Section
Immunobiology Study Section (IMB)
Project Start
1991-03-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Doerre, Stefan; Mesires, Kristin Perkins; Daley, Kylle M et al. (2005) Reductions in I kappa B epsilon and changes in NF-kappa B activity during B lymphocyte differentiation. J Immunol 174:983-91
Corley, R B; Morehouse, E M; Ferguson, A R (2005) IgM accelerates affinity maturation. Scand J Immunol 62 Suppl 1:55-61
Ferguson, Andrew R; Corley, Ronald B (2005) Accumulation of marginal zone B cells and accelerated loss of follicular dendritic cells in NF-kappaB p50-deficient mice. BMC Immunol 6:8
Ferguson, Andrew R; Youd, Michele E; Corley, Ronald B (2004) Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int Immunol 16:1411-22
Flemming, Jennifer A; Perkins, Kristin H; Luus, Lia et al. (2004) Disruption of membrane cholesterol stimulates MyD88-dependent NF-kappaB activation in immature B cells. Cell Immunol 229:68-77
Youd, Michele E; Ferguson, Andrew R; Corley, Ronald B (2002) Synergistic roles of IgM and complement in antigen trapping and follicular localization. Eur J Immunol 32:2328-37
Reddy, P S; Corley, R B (1999) The contribution of ER quality control to the biologic functions of secretory IgM. Immunol Today 20:582-8
Doerre, S; Corley, R B (1999) Constitutive nuclear translocation of NF-kappa B in B cells in the absence of I kappa B degradation. J Immunol 163:269-77
Reddy, P S; Corley, R B (1998) Assembly, sorting, and exit of oligomeric proteins from the endoplasmic reticulum. Bioessays 20:546-54
Hughey, C T; Brewer, J W; Colosia, A D et al. (1998) Production of IgM hexamers by normal and autoimmune B cells: implications for the physiologic role of hexameric IgM. J Immunol 161:4091-7

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