Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI031478-06
Application #
2066436
Study Section
Special Emphasis Panel (ZRG5-TMP (01))
Project Start
1991-08-01
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Genetics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Baia-da-Silva, Djane Clarys; Alvarez, Luis Carlos Salazar; Lizcano, Omaira Vera et al. (2018) The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis. Parasit Vectors 11:148
Wang, Sibao; Dos-Santos, André L A; Huang, Wei et al. (2017) Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria. Science 357:1399-1402
Orfano, Alessandra S; Nacif-Pimenta, Rafael; Duarte, Ana P M et al. (2016) Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites. Malar J 15:394
Goodman, Christopher D; Siregar, Josephine E; Mollard, Vanessa et al. (2016) Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes. Science 352:349-53
McLean, Kyle Jarrod; Jacobs-Lorena, Marcelo (2016) Genetic Control Of Malaria Mosquitoes. Trends Parasitol 32:174-176
Vega-Rodriguez, Joel; Perez-Barreto, Davinia; Ruiz-Reyes, Antonio et al. (2015) Targeting molecular interactions essential for Plasmodium sexual reproduction. Cell Microbiol 17:1594-604
Ferrer, Patricia; Vega-Rodriguez, Joel; Tripathi, Abhai K et al. (2015) Antimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition. Antimicrob Agents Chemother 59:1418-26
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Smith, Ryan C; Barillas-Mury, Carolina; Jacobs-Lorena, Marcelo (2015) Hemocyte differentiation mediates the mosquito late-phase immune response against Plasmodium in Anopheles gambiae. Proc Natl Acad Sci U S A 112:E3412-20
Smith, Ryan C; Jacobs-Lorena, Marcelo (2015) Malaria parasite Pfs47 disrupts JNK signaling to escape mosquito immunity. Proc Natl Acad Sci U S A 112:1250-1

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